Results 181 to 190 of about 32,200 (252)

Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents

Brain and Behavior, Volume 16, Issue 6, June 2026.
In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence, Daniel Fulton, Poppy Brown, Subashini Suresh, Mark Morris, Paraskevi Goggolidou, Sree Chaithanya, Marcus Abbawy, Amelia Wild, Prashant Nasa, Niharika A. Duggal, Fang Gao‐Smith, Zubair Ahmed, Suresh Renukappa, Tonny Veenith   +14 more
wiley   +1 more source

Early Behavioral and Cognitive Changes in Patients With Pathologically Confirmed Alzheimer Disease, Lewy Body Dementia, and Mixed Dementia. [PDF]

Neurol Open Access
Wang M, Wu H, Bonner-Jackson A, Chen Y, Tang W, Feng H, Zhang L, Chen C, Leverenz JB, Pillai JA.   +9 more
europepmc   +1 more source

Health‐care use before suicide among older adults with newly diagnosed dementia in a national Medicare cohort

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract Introduction Older adults recently diagnosed with dementia face elevated short‐term suicide risk, yet little is known about their ensuing contact with the health‐care system prior to suicide. METHODS Medicare claims from 2012 to 2015 linked to the National Death Index were used to examine the timing and type of service use among 824 ...
Timothy Schmutte, Mark Olfson, Ming Xie, Steven C. Marcus   +3 more
wiley   +1 more source

Cohort profile: a community‐based prospective cohort study of Alzheimer's disease and related dementias in the Democratic Republic of Congo

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract INTRODUCTION The Étude du Vieillissement Cognitif et de Démence en République Démocratique du Congo (EVCD‐RDC) launched in 2024 to investigate socio‐environmental and biological determinants of dementia in Kinshasa. METHODS The study recruited 1000 adults aged ≥65 years across four diagnostic groups – cognitively unimpaired (CU), mild ...
Jean Ikanga, Caterina Obenauf, Saranya Sundaram Patel, Megan Schwinne, Guy Gikelekele, Emmanuel Epenge, Japhet Magolu Potshi, Topina Tomadia, Julie Kazadi, Immaculee Kavugho, Giovanni Luamba Santolini, Aristote Nkosi, Francine Manyonga Sabowa, Brenda Matungu Musewu, Elipsis Mawisa, Joseph Phuati Tsangu, Francis Muena Kondo Beya, Samuel Mampunza, Lelo Mananga, Justine Bukabau, Charlotte E. Teunissen, Thomas Karikari, Alden L. Gross, Julio C. Rojas, Alvaro Alonso   +24 more
wiley   +1 more source

Alpha‐tACS Improves Executive Function and Alpha Power Spectral Density in Patients With Post‐Stroke Cognitive Impairment

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
We applied alpha‐frequency transcranial alternating current stimulation (alpha‐tACS) to treat post‐stroke cognitive impairment. A 4‐week intervention significantly improved cognitive scores and executive function while enhancing alpha oscillations across cortical networks.
Weicheng Kong, Jian Song, Yanyan Li, Yuqing Zhao, Xinyang Wang, Haoran Shi, Jiayu Cai, Wei Wei, Xiehua Xue   +8 more
wiley   +1 more source

Progress of Immunotherapies in Parkinson's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Parkinson's disease (PD) is caused by an immune disorder triggered by α‐synuclein, leading to a persistent neuroinflammatory cycle that drives the disease from non‐motor symptoms to the motor stage. Second, it presents active and passive immunotherapy strategies targeting α‐synuclein and their potential in slowing down the disease progression.
Yong Peng, Xu‐hui Kang, Shun‐yu Yao, Xiuli Zhang, Sugimoto Kazuo, Jia Liu, Miao‐qiao Du, Lan‐xin Lin, Dai‐yi Jiang, Quan Chen, Hong Jin   +10 more
wiley   +1 more source

Safety and efficacy of pimavanserin in patients with Lewy body dementia experiencing dementia-related psychosis in the HARMONY study. [PDF]

BMC Neurol
Torres-Yaghi Y, Chrones L, Abler V, Brunson G.   +3 more
europepmc   +1 more source

Exercise Intervention for REM Sleep Behavior Disorder in Parkinson's Disease: Mechanisms and Implications for Neurorehabilitation

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This review systematically explores exercise as a multi‐target intervention for RBD, highlighting its mechanisms of action and regulatory effects on key pathophysiological processes. ABSTRACT Backgrounds REM sleep behavior disorder (RBD) is a prodromal non‐motor symptom of Parkinson's disease (PD) and other α‐synucleinopathies, affecting approximately ...
Xinhui Qiu, Zihui Wang, Ruixue Xu, Yiying Hu, Weidong Le   +4 more
wiley   +1 more source