Results 31 to 40 of about 56,171 (221)
The Alzheimer variant of Lewy body disease: A pathologically confirmed case-control study [PDF]
The objective of the study was to identify clinical features that distinguish patients with dementia with Lewy bodies (DLB), who were classified as Alzheimer's disease ( AD) patients, from patients with AD.
Busch, R. +7 more
core +1 more source
This article provides an overview of the clinical features, neuropathologic findings, diagnostic criteria, and management of dementia with Lewy bodies (DLB) and Parkinson disease dementia (PDD), together known as the Lewy body dementias.DLB and PDD are common, clinically similar syndromes that share characteristic neuropathologic changes, including ...
openaire +2 more sources
What Can Quantitative Gait Analysis Tell Us about Dementia and Its Subtypes? A Structured Review [PDF]
Distinguishing dementia subtypes can be difficult due to similarities in clinical presentation. There is increasing interest in discrete gait characteristics as markers to aid diagnostic algorithms in dementia.
Galna, Brook +5 more
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A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease
Lewy body diseases are neurodegenerative disorders characterized by Lewy bodies in the brain. Lewy body dementia (LBD) refers to two forms of Lewy body disease: Parkinson’s disease with dementia (PDD) and dementia with Lewy bodies (DLB).
Benjamin R. Smith +6 more
doaj +1 more source
Non-pharmacological interventions for Lewy body dementia: a systematic review. [PDF]
Lewy body dementia (consisting of dementia with Lewy bodies and Parkinson's disease dementia) is a common neurodegenerative disease characterised by visual hallucinations, fluctuating attention, motor disturbances, falls, and sensitivity to ...
Allan, Louise +8 more
core +1 more source
Clinicopathological Correlates of Lewy Body Disease: Fundamental Issues [PDF]
Lewy body pathology (LBP) is the pathological hallmark of Lewy body diseases, such as Parkinson’s disease and Lewy body dementia. Recent studies have shed new light on the role of LBP, the interactions of LBP with concomitant pathologies, and the ...
Tae-Beom Ahn
doaj +1 more source
Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience [PDF]
Background: Dementia results from heterogeneous diseases of the brain. Mixed disease forms are increasingly recognized. Methods: We performed a survey within brain banks of BrainNet Europe to estimate the proportion of mixed disease forms underlying ...
Al-Sarraj, Safa +15 more
core +1 more source
Neuropathology and molecular diagnosis of Synucleinopathies
Synucleinopathies are clinically and pathologically heterogeneous disorders characterized by pathologic aggregates of α-synuclein in neurons and glia, in the form of Lewy bodies, Lewy neurites, neuronal cytoplasmic inclusions, and glial cytoplasmic ...
Shunsuke Koga +4 more
doaj +1 more source
The (ANTI)psychotic paradox: Lewy body dementia
Introduction Lewy Bodie Dementia (LBD) is the second more common progressive dementia caused by the deposition of proteins at the neocortical level, producing motor and psychotic symptoms (parkinsonism and visual hallucinations) which typically get ...
J. Galvañ, I. Angélico
doaj +1 more source
Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. [PDF]
The gold standard for a definitive diagnosis of Parkinson disease (PD) is the pathologic finding of aggregated α-synuclein into Lewy bodies and for Alzheimer disease (AD) aggregated amyloid into plaques and hyperphosphorylated tau into tangles.
Brundin, P +26 more
core +3 more sources

