Results 41 to 50 of about 32,258 (154)

Update on Dementia with Lewy Bodies [PDF]

Current Translational Geriatrics and Experimental Gerontology Reports, 2013
Dementia with Lewy bodies (DLB) is the second most common form of dementia after Alzheimer disease (AD). DLB is characterized pathologically by Lewy body and Lewy neuritic pathology, often with variable levels of Alzheimer-type pathology. Core clinical features include fluctuating cognition, visual hallucinations, and parkinsonism resulting in greater ...
Stella, Karantzoulis, James E, Galvin
openaire   +2 more sources

Decision-making for receiving paid home care for dementia in the time of COVID-19: a qualitative study

BMC Geriatrics, 2020
Background The lockdown imposed in the UK on the 23rd of March and associated public health measures of social distancing are likely to have had a great impact on care provision.
Clarissa Giebel, Kerry Hanna, Jacqueline Cannon, Ruth Eley, Hilary Tetlow, Anna Gaughan, Aravind Komuravelli, Justine Shenton, Carol Rogers, Sarah Butchard, Steve Callaghan, Stan Limbert, Manoj Rajagopal, Kym Ward, Lisa Shaw, Rosie Whittington, Mishca Hughes, Mark Gabbay   +17 more
doaj   +1 more source

Parkinson’s Disease and Dementia with Lewy Bodies: One and the Same

Journal of Parkinson’s Disease
The question whether Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) are expressions of the same underlying disease has been vigorously debated for decades.
Per Borghammer, Niels Okkels, Daniel Weintraub   +2 more
doaj   +1 more source

GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson's Disease and Lewy Body Dementia.

PLoS ONE, 2016
Based on animal and ex-vivo experiments, Growth/Differentiation Factor-15 (GDF15, also called Macrophage Inhibitory Cytokine-1, MIC1), a member of the transforming growth factor-beta family, and Matrix Metalloproteinase-9 (MMP9), a member of the matrix ...
Walter Maetzler, Willy Deleersnijder, Valérie Hanssens, Alice Bernard, Kathrin Brockmann, Justus Marquetand, Isabel Wurster, Tim W Rattay, Lorenzo Roncoroni, Eva Schaeffer, Stefanie Lerche, Anja Apel, Christian Deuschle, Daniela Berg   +13 more
doaj   +1 more source

Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis

Parkinson's Disease, 2012
Dementia is a common feature in Parkinson’s disease (PD) and is considered to be the result of limbic and cortical Lewy bodies and/or Alzheimer changes.
Simone A. van den Berge, Josta T. Kevenaar, Jacqueline A. Sluijs, Elly M. Hol   +3 more
doaj   +1 more source

Retinal and Cortical Visual Processing Dysfunction in a Case of Mild Cognitive Impairment with Lewy Bodies: A Case Report

Journal of Alzheimer's Disease Reports
The prodromal stage of Lewy body dementia includes a mild cognitive impairment with visual processing and/or attention-executive deficits. A clinical presentation with progressive visual loss is indeed seldom reported and can be misleading with a ...
Giulia Perini, Matteo Cotta Ramusino, Francesca Conca, Giuseppe Cosentino, Lisa Maria Farina, Alfredo Costa, Elisabetta Farina   +6 more
doaj   +1 more source

Case Report: Lewy body dementia with unusual psychotic symptoms, atypically late parkinsonism, and patient sensitivity to first generation antipsychotics

Frontiers in Psychiatry
Lewy body dementia is associated with abnormal eosinophilic A-synuclein neural inclusions (Lewy bodies) in the brain. It is a neurodegenerative illness—and the second most common type of dementia after Alzheimer’s disease—that causes memory loss and ...
Lolita Ercika, Lolita Ercika, Maris Taube, Maris Taube, Maris Taube   +4 more
doaj   +1 more source

An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias

Molecular Brain, 2017
Lewy body dementias are the second most common cause of neurodegenerative dementia in the elderly after Alzheimer’s disease (AD). The two clinical subgroups of Lewy body dementias, namely, dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (
Arnab Datta, Yuek Ling Chai, Jing Min Tan, Jasinda H. Lee, Paul T. Francis, Christopher P. Chen, Siu Kwan Sze, Mitchell K. P. Lai   +7 more
doaj   +1 more source

Sex differences for regional pathology in people with a high likelihood of Lewy body dementia phenotype based on underlying pathology

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Introduction Clinicopathological correlations differ by sex in Lewy body dementia (LBD). However, previous studies have focused on pathological staging systems that place less emphasis on regional pathologies.
Ece Bayram, David G. Coughlin, Shunsuke Koga, Owen A. Ross, Irene Litvan, Dennis W. Dickson   +5 more
doaj   +1 more source

Network hierarchy in Alzheimer’s and Lewy body spectrum disorders: functional gradients, cognitive phenotypes, and translational gaps

Frontiers in Aging Neuroscience
Dementia syndromes alter cortical hierarchy in addition to individual brain regions. Functional connectivity gradients offer a continuous, low-dimensional framework for examining these hierarchy-level changes.
Yujian Liu, Tianjiao Lv, Yuan Li
doaj   +1 more source