Results 61 to 70 of about 33,574 (228)

Retinal and Cortical Visual Processing Dysfunction in a Case of Mild Cognitive Impairment with Lewy Bodies: A Case Report

Journal of Alzheimer's Disease Reports
The prodromal stage of Lewy body dementia includes a mild cognitive impairment with visual processing and/or attention-executive deficits. A clinical presentation with progressive visual loss is indeed seldom reported and can be misleading with a ...
Giulia Perini, Matteo Cotta Ramusino, Francesca Conca, Giuseppe Cosentino, Lisa Maria Farina, Alfredo Costa, Elisabetta Farina   +6 more
doaj   +1 more source

Case Report: Lewy body dementia with unusual psychotic symptoms, atypically late parkinsonism, and patient sensitivity to first generation antipsychotics

Frontiers in Psychiatry
Lewy body dementia is associated with abnormal eosinophilic A-synuclein neural inclusions (Lewy bodies) in the brain. It is a neurodegenerative illness—and the second most common type of dementia after Alzheimer’s disease—that causes memory loss and ...
Lolita Ercika, Lolita Ercika, Maris Taube, Maris Taube, Maris Taube   +4 more
doaj   +1 more source

Limbic Structural Alterations and Structural Covariance Across Prodromal Phenotypes and Early Parkinson's Disease

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Non‐motor symptoms may precede motor diagnosis in Parkinson's disease (PD), but whether distinct prodromal phenotypes exhibit differential limbic structural alterations remains unclear. Purpose To investigate limbic structural alterations across prodromal PD phenotypes defined by rapid eye movement sleep behavior disorder (RBD) and ...
Yuanyuan Zhao, Luoyu Wang, Yihan Suo, Maoling Liu, Yi Lin, Lidan Fang, Zhongxiang Ding   +6 more
wiley   +1 more source

An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias

Molecular Brain, 2017
Lewy body dementias are the second most common cause of neurodegenerative dementia in the elderly after Alzheimer’s disease (AD). The two clinical subgroups of Lewy body dementias, namely, dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (
Arnab Datta, Yuek Ling Chai, Jing Min Tan, Jasinda H. Lee, Paul T. Francis, Christopher P. Chen, Siu Kwan Sze, Mitchell K. P. Lai   +7 more
doaj   +1 more source

Vocal Fold Atrophy in Patients With Alzheimer's Disease and Related Dementias

The Laryngoscope, EarlyView.
This is the first study to quantify vocal fold atrophy in patients with Alzheimer's disease and related dementias (AD/ADRD) using endoscopic imaging. Compared with age‐matched controls, AD/ADRD patients showed significantly greater vocal fold bowing and reduced mucosal wave amplitude, while normalized glottal gap area did not differ.
Byron Kim, Carson Miller, Shruti Dhingra, Mahdi Al‐Ghezi, Emily Wilson, Neel K. Bhatt   +5 more
wiley   +1 more source

Alzheimer's Disease Beyond Amyloid: Lessons From Atherosclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Marcello Ciaccio, Luisa Agnello
wiley   +1 more source

Mind the Gap: Predictors of Osteoporosis Treatment Following Fragility Fracture in Parkinsonism

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Fracture risk is increased in Parkinson's yet this risk is often not addressed. Objectives Our objective was to study the extent to which osteoporosis was treated, and predictors of treatment in a large representative cohort with parkinsonism.
Katie C. Naylor, Emily J. Henderson, Emma Tenison   +2 more
wiley   +1 more source

Sex differences for regional pathology in people with a high likelihood of Lewy body dementia phenotype based on underlying pathology

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Introduction Clinicopathological correlations differ by sex in Lewy body dementia (LBD). However, previous studies have focused on pathological staging systems that place less emphasis on regional pathologies.
Ece Bayram, David G. Coughlin, Shunsuke Koga, Owen A. Ross, Irene Litvan, Dennis W. Dickson   +5 more
doaj   +1 more source

Network hierarchy in Alzheimer’s and Lewy body spectrum disorders: functional gradients, cognitive phenotypes, and translational gaps

Frontiers in Aging Neuroscience
Dementia syndromes alter cortical hierarchy in addition to individual brain regions. Functional connectivity gradients offer a continuous, low-dimensional framework for examining these hierarchy-level changes.
Yujian Liu, Tianjiao Lv, Yuan Li
doaj   +1 more source

Cardiac MIBG Scintigraphy in Neurodegenerative Parkinsonism: Limitations in Clinical Practice

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Reduced cardiac uptake on 123Iodine‐metaiodobenzylguanidine (MIBG) scintigraphy is a valuable tool for differentiating neurodegenerative parkinsonism but interpretation can be difficult due to comorbidities and drug‐tracer interactions.
Frank Jagusch, Elena Redl, Christoph Theyer, Atbin Djamshidian, Alessandra Fanciulli, Werner Poewe, Philipp Mahlknecht, Beatrice Heim, Klaus Seppi, Florian Krismer   +9 more
wiley   +1 more source