Abstract Dementia constitutes one of the most widespread neurological disorders, representing an important health concern due to its increasing prevalence. Among the various types of dementia, Alzheimer's disease (AD) is the most common in the elderly, characterized by episodic memory impairment and also a decline in executive functions. Mild cognitive
Luis Heredia +3 more
wiley +1 more source
Cholinergic white matter pathways integrity in prodromal and early manifest Lewy body disease. [PDF]
Eisenstein T +9 more
europepmc +1 more source
The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease [PDF]
Bateman, Randall J +5 more
core +1 more source
The Effect of Deep Brain Stimulation on Sleep and Cognition in Patients With Parkinson's Disease
ABSTRACT Sleep–wake disturbances and cognitive decline are among the most common nonmotor symptoms of Parkinson's disease (PD). Deep brain stimulation (DBS) can successfully alleviate motor symptoms. However, the impact on sleep–wake disturbances and cognitive decline, and their interaction, is yet unclear.
Monique E. H. Valk‐Geuke +5 more
wiley +1 more source
Reliability and modeling of digital histological measurements in Alzheimer's disease neuropathologic change and Lewy body disease. [PDF]
Kim Y +7 more
europepmc +1 more source
Talking therapies for anxiety and depression in people affected by dementia: A scoping meta‐review
Abstract Background Symptoms of anxiety and depression are common in people affected by dementia (people with dementia and family carers). There are many reviews of psychological interventions to reduce stress and distress in people with dementia and family carers, but little cross‐fertilisation with the evidence base underpinning NHS Talking Therapies
Georgina Charlesworth +2 more
wiley +1 more source
Skin Biopsy for Phosphorylated α-Synuclein in Mild Cognitive Impairment or Dementia Due to Lewy Body Disease in a Convenience Cohort from a Subspecialty Behavioral Neurology Practice. [PDF]
Rigby MJ +24 more
europepmc +1 more source
Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda +4 more
wiley +1 more source
Blood microbiome signatures in the REM sleep behavior disorder-Lewy body disease continuum. [PDF]
Kim R +5 more
europepmc +1 more source
Optimization of photobiomodulation therapy for spinal cord injury: A review
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew +3 more
wiley +1 more source

