ABSTRACT Background Cognitive impairment, including dementia, is one of the most important nonmotor symptoms of Parkinson's disease (PD). It lowers quality of life and impacts health and economic outcomes for individuals living with PD, their families, and society.
Deepa Sriram +12 more
wiley +1 more source
Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline. [PDF]
Wood Alexander M +17 more
europepmc +1 more source
ABSTRACT Aims To identify and evaluate the magnitude of the association between caregiver psychosocial factors and depressive symptoms among people with dementia. Design Systematic review and meta‐analysis. Methods A systematic review with meta‐analysis used a random‐effects model to estimate the effect size.
Wenjing Ning +3 more
wiley +1 more source
RETRACTION: α-Synuclein Conformational Antibodies Fused to Penetratin are Effective in Models of Lewy Body Disease. [PDF]
europepmc +1 more source
Minor Visual Phenomena in Lewy Body Disease: A Systematic Review. [PDF]
Capogna E +10 more
europepmc +1 more source
The Effect of Deep Brain Stimulation on Sleep and Cognition in Patients With Parkinson's Disease
ABSTRACT Sleep–wake disturbances and cognitive decline are among the most common nonmotor symptoms of Parkinson's disease (PD). Deep brain stimulation (DBS) can successfully alleviate motor symptoms. However, the impact on sleep–wake disturbances and cognitive decline, and their interaction, is yet unclear.
Monique E. H. Valk‐Geuke +5 more
wiley +1 more source
Hypometabolic mismatch with atrophy and tau pathology in mixed Alzheimer's and Lewy body disease. [PDF]
Duong MT +12 more
europepmc +1 more source
ABSTRACT Fragile X‐associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder characterized by a late onset and slow progression caused by a premutation (55–200 CGG repeat) in the fragile X mental retardation (FMR1) gene. Here, we report the case of a Japanese patient with FXTAS which is the first case autopsied in Japan. The patient was
Ayako Shioya +5 more
wiley +1 more source
Late-Onset Oral Cenesthopathy With Dopaminergic Dysfunction: Therapeutic Response to Pramipexole in a Case With Suspected Prodromal Lewy Body Disease. [PDF]
Matsui H +7 more
europepmc +1 more source
Recent Insights Into Alzheimer's Disease: Advances in Pathophysiology and Therapeutic Strategies
ABSTRACT Alzheimer's disease (AD) is a complex neurodegenerative disorder driven by interplay among amyloid‐β (Aβ) plaques, tau neurofibrillary tangles, inflammation and comorbid pathologies. Recent advances in biomarkers and therapeutic approvals have reshaped our understanding of its pathophysiology and treatment landscape.
Jiong Shi +3 more
wiley +1 more source

