Results 221 to 230 of about 72,473 (300)
Donepezil research in cognitive impairment: a bibliometric and scientometric analysis. ABSTRACT Background Cognitive impairment (CI) greatly affects global health and quality of life. Donepezil, a widely used treatment for CI, particularly in Alzheimer's disease, has been extensively studied; however, a comprehensive bibliometric analysis summarizing ...
Wencai Wang +5 more
wiley +1 more source
High prevalence of atrial conduction abnormalities in Lewy body disease - a marker of cardiac complications? [PDF]
Javanshiri K +3 more
europepmc +1 more source
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés +13 more
wiley +1 more source
ABSTRACT Objectives Aggressive behaviour and decreased empathy occur in many dementia syndromes. This may be related to lowered overall cognitive functioning which is a common feature of dementia. However, to date, the role of social cognitive impairments such as facial emotion recognition (FER) deficits in dementias other than behavioural variant ...
Aafra T. Ter Horst +2 more
wiley +1 more source
Early Motor Signs in Pathologically Verified Alzheimer's Disease and Lewy Body Disease. [PDF]
Oh DM +7 more
europepmc +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Heat shock protein 10 as a chaperone modulating α‐synuclein amyloid fibril formation
Abstract HSP10 is a well‐known human co‐chaperone that interacts with HSP60 to comprise the HSP60/10 chaperonin complex which upholds mitochondrial proteostasis. HSP10 also demonstrates independent roles in binding to misfolded proteins and interacts with several amyloidogenic client proteins.
Johan N. K. Larsson +5 more
wiley +1 more source
Aberrant accumulation of phosphorylated BRCA1 in brainstem-type and cortical-type Lewy bodies in Lewy body disease. [PDF]
Nakamura M +3 more
europepmc +1 more source

