Results 11 to 20 of about 11,952,476 (292)

Sirt1 and Nrf2: regulation of Leydig cell oxidant/antioxidant intracellular environment and steroid formation

open access: yesBiology of Reproduction, 2021
Previous studies reported that, with aging, Leydig cell intracellular antioxidants are reduced in concentration and intracellular ROS levels increase, suggesting that oxidant/antioxidant imbalance may contribute to the reduced testosterone production ...
Jin-Yong Chung, Haolin Chen, B. Zirkin
semanticscholar   +1 more source

Triadimefon increases fetal Leydig cell proliferation but inhibits its differentiation of male fetuses after gestational exposure

open access: yesEcotoxicology and Environmental Safety, 2021
Triadimefon is a broad-spectrum fungicide widely applied in the agriculture. It is believed to be an endocrine disruptor. Whether triadimefon can inhibit the development of fetal Leydig cells and the underlying mechanisms are unknown.
Liben Lin   +9 more
doaj   +1 more source

Fetal Leydig cells in buffalo testis: Light and electron microscopic study

open access: yesIndian Journal of Animal Sciences, 2020
The present study was conducted on testis of 20 buffalo fetuses ranging from 2.5 cm to 20 cm curved crown rump length (CVRL). The tissues were processed for light and transmission electron microscopic study.
INDERPREET SINGH   +4 more
doaj   +1 more source

Role of antioxidant to protect Leydig cells induced by reactive oxygen species: a literature review

open access: yesQanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2021
The Leydig cells play crucial role in steroidogenesis and spermatogenesis. Those processes need complex communication in hormonal and testicular to maintain male reproductive function.
Anak Agung Istri Dalem Cinthya Riris   +2 more
doaj   +1 more source

Bisphenols and Leydig Cell Development and Function

open access: yesFrontiers in Endocrinology, 2020
Bisphenol A (BPA) is a ubiquitous environmental pollutant, mainly from the production and use of plastics and the degradation of wastes related to industrial plastics.
Xiaoheng Li   +5 more
semanticscholar   +1 more source

Quantitation of Leydig Cell in Testicular Biopsies of Gossypol Treated rats

open access: yesThe Iraqi Journal of Veterinary Medicine, 2005
Leydig cell density was evaluated quantitatively in bilateral testicular biopsies from twenty male rats of two equal groups Gossypol treated and control.
Muhannad A. A. Al Bayaty
doaj   +1 more source

TRPV1 activation induces cell death of TM3 mouse Leydig cells

open access: yesJournal of Animal Reproduction and Biotechnology, 2021
The role of transient receptor potential vanilloid receptor-1 (TRPV1) has been primarily investigated in pain sensory neurons. Relatively, little research has been performed in testicular cells.
Eun-Jin Kim   +6 more
doaj   +1 more source

Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]

open access: yes, 2009
Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H.   +4 more
core   +1 more source

Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death. [PDF]

open access: yes, 2015
Leydig cells are crucial to the production of testosterone in males. It is unknown if the cancer chemotherapeutic drug, 6-mercaptopurine (6 MP), produces Leydig cell failure among adult survivors of childhood acute lymphoblastic leukemia. Moreover, it is
Bao, Ju   +11 more
core   +1 more source

Fibroblast Growth Factor 1 Promotes Rat Stem Leydig Cell Development

open access: yesFrontiers in Endocrinology, 2019
Fibroblast growth factor 1 (FGF1) is reported to be expressed in the testis. How FGF1 affects stem Leydig cell development remains unclear. Here, we report the effects of FGF1 on rat stem Leydig cell development in an ethane dimethane sulfonate (EDS ...
Lanlan Chen   +14 more
doaj   +1 more source

Home - About - Disclaimer - Privacy