Role of Constitutive STAR in Leydig Cells
International Journal of Molecular Sciences, 2021 Leydig cells contain significant amounts of constitutively produced steroidogenic acute regulatory protein (STAR; STARD1). Hormone-induced STAR plays an essential role in inducing the transfer of cholesterol into the mitochondria for hormone-dependent ...
M. Galano +4 more
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Differentiation of adult-type Leydig cells occurs in gonadotrophin-deficient mice [PDF]
, 2003 During mammalian testis development distinct generations of fetal and adult Leydig cells arise. Luteinising hormone (LH) is required for normal adult Leydig cell function and for the establishment of normal adult Leydig cell number but its role in the ...
Baker, P.J. +4 more
core +9 more sources
Cell Death and Disease, 2022 Cadmium is one of the environmental and occupational pollutants and its potential adverse effects on human health have given rise to substantial concern. Cadmium causes damage to the male reproductive system via induction of germ-cell apoptosis; however,
Ling-Na Yi +8 more
semanticscholar +1 more source
Aristaless related homeobox gene, Arx, is implicated in mouse fetal Leydig cell differentiation possibly through expressing in the progenitor cells. [PDF]
PLoS ONE, 2013 Development of the testis begins with the expression of the SRY gene in pre-Sertoli cells. Soon after, testis cords containing Sertoli and germ cells are formed and fetal Leydig cells subsequently develop in the interstitial space. Studies using knockout
Kanako Miyabayashi +7 more
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Fetal Leydig cells in buffalo testis: Light and electron microscopic study
Indian Journal of Animal Sciences, 2020 The present study was conducted on testis of 20 buffalo fetuses ranging from 2.5 cm to 20 cm curved crown rump length (CVRL). The tissues were processed for light and transmission electron microscopic study.
INDERPREET SINGH +4 more
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Involvement of p38 MAPK in Leydig cell aging and age-related decline in testosterone
Frontiers in Endocrinology, 2023 IntroductionAge-related decline in testosterone is associated with Leydig cell aging with impaired testosterone synthesis in aging. Obesity accelerates the age-related decline in testosterone.
Dandan Luo +10 more
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Isolation of Primary Leydig Cells from Murine Testis
Bio-Protocol, 2021 In males, Leydig cells are the primary source of testosterone, which is necessary for testis development, masculinization, and spermatogenesis. Leydig cells are a valuable cellular model for basic research; thus, it is important to develop an improved ...
Jinlian Liang +8 more
doaj +1 more source
Role of antioxidant to protect Leydig cells induced by reactive oxygen species: a literature review
Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2021 The Leydig cells play crucial role in steroidogenesis and spermatogenesis. Those processes need complex communication in hormonal and testicular to maintain male reproductive function.
Anak Agung Istri Dalem Cinthya Riris +2 more
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Effects of main compositions of Astragalus on estradiol synthesizing activing in TGF-β1-induced rat testicular Leydig cell line [PDF]
Jichu yixue yu linchuang, 2021 Objective To investigate the effects of the main compositions of Astragalus on testicular Leydig cells and their synthesis of estradiol(E2), P450arom under TGF-β1 induction.
LI Yan-rong, LIU Guang-wei, ZHAO Jing, LI Ya-jun
doaj
Quantitation of Leydig Cell in Testicular Biopsies of Gossypol Treated rats
The Iraqi Journal of Veterinary Medicine, 2005 Leydig cell density was evaluated quantitatively in bilateral testicular biopsies from twenty male rats of two equal groups Gossypol treated and control.
Muhannad A. A. Al Bayaty
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