Results 31 to 40 of about 16,604,758 (298)
Brazilian Journal of Medical and Biological Research, 2002 Plasma and tissue testosterone concentrations were determined by radioimmunoassay in 12 eight-month-old sexually mature New Zealand White rabbits and evaluated for possible associations with spermatogenic efficiency as well as with volume density and ...
A.C.S. Castro +2 more
doaj +1 more source
European Journal of Histochemistry, 2009 A broad expression of aromatase and estrogen receptors (ERs) in the testis suggests an important role for estrogens in regulating testicular cell function and reproductive events.
M Kotula-Balak +3 more
doaj +1 more source
FOXA3, a Negative Regulator of Nur77 Expression and Activity in Testicular Steroidogenesis
International Journal of Endocrinology, 2021 Biosynthesis of testosterone occurs mainly in the testicular Leydig cells. Nur77, an orphan nuclear receptor that is expressed in response to the luteinizing hormone/cyclic adenosine monophosphate (LH/cAMP) signaling pathway, is one of the key factors ...
Hansle Kim, Sudeep Kumar, Keesook Lee
doaj +1 more source
Fibroblast growth factor 9 activates akt and MAPK pathways to stimulate steroidogenesis in mouse leydig cells. [PDF]
PLoS ONE, 2014 Fibroblast growth factor 9 (FGF9) is a multifunctional polypeptide belonging to the FGF family and has functions related to bone formation, lens-fiber differentiation, nerve development, gap-junction formation and sex determination.
Meng-Shao Lai +4 more
doaj +1 more source
Leydig Cells in Patients with Non-Obstructive Azoospermia: Do They Really Proliferate?
Life, 2021 Background: Non-obstructive azoospermia (NOA) is a form of male infertility caused by disorders of the testicular parenchyma and impaired spermatogenesis.
Dinko Hauptman +7 more
doaj +1 more source
Leydig cells express neural cell adhesion molecules in vivo and in vitro [PDF]
, 1992 The neural cell adhesion molecule (NCAM) polypeptides are expressed by numerous tissues during embryonic development, where they are involved in cell-cell interactions.
Lahr, G. +7 more
core +1 more source
Cell Death and Disease, 2019 Adrenomedullin (ADM) exerts anti-oxidant, anti-inflammatory and anti-apoptotic effects in Leydig cells. However, the role and mechanism of ADM in the pyroptosis of Leydig cells are poorly understood.
Ming-yong Li +11 more
semanticscholar +1 more source
Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]
, 2010 Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel +5 more
core +1 more source
Testicular development in mice lacking receptors for follicle stimulating hormone and androgen [PDF]
, 2012 Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Abel, M. +11 more
core +2 more sources
Jurnal Kedokteran Hewan, 2018 The aim of this study was to evaluate the ability of rat’s Leydig cells collected with Nycodenz gradient in producing testosterone in vitro. Leydig cells were collected using 5 column of Nycodenz gradient (4, 8, 10, 12, and 15%) and cells were evaluated ...
Ekayanti Mulyawati Kaiin +1 more
doaj +1 more source