Results 41 to 50 of about 11,867 (232)

BPA-Induced Deregulation of Epigenetic Patterns: Effects on Female Zebrafish Reproduction [PDF]

, 2016
Bisphenol A (BPA) is one of the commonest Endocrine Disruptor Compounds worldwide. It interferes with vertebrate reproduction, possibly by inducing deregulation of epigenetic mechanisms.
Carnevali, Oliana, Cobellis, Gilda, DALLA VALLE, Luisa, Gioacchini, Giorgia, Maradonna, Francesca, Piccinetti, Chiara Carla, Santangeli, Stefania   +6 more
core   +1 more source

Influence of VEGFR and LHCGR on endometrial adenocarcinoma

Oncology Letters, 2016
Endometrial adenocarcinoma is a common gynecological malignancy that is usually treated by surgical resection followed by radiation. However, the frequency of remote metastasis is high. The present study aimed to investigate whether patients with endometrial adenocarcinoma exhibited a positive response to treatment with a gonadotropin-releasing hormone
Ulrich Andergassen, Udo Jeschke, Amelie E. Birk, Christina Kuhn, Alexandra C. Kölbl   +4 more
openaire   +4 more sources

Luteinizing Hormone and GATA4 Action in the Adrenocortical Tumorigenesis of Gonadectomized Female Mice

Cellular Physiology and Biochemistry, 2017
Background/Aims: Physiological role of luteinizing hormone (LH) and its receptor (LHCGR) in adrenal remains unknown. In inhibin-α/Simian Virus 40 T antigen (SV40Tag) (inhα/Tag) mice, gonadectomy-induced (OVX) elevated LH triggers the growth of ...
Milena Doroszko, Marcin Chrusciel, Joanna Stelmaszewska, Tomasz Slezak, Adolfo Rivero-Muller, Artur Padzik, Slawomir Anisimowicz, Slawomir Wolczynski, Ilpo Huhtaniemi, Jorma Toppari, Nafis A. Rahman   +10 more
doaj   +1 more source

Novel functions of the luteinizing hormone/chorionic gonadotropin receptor in prostate cancer cells and patients.

PLoS ONE, 2020
Prostate cancer (PCa) cells become castrate-resistant after initial tumor regression following castration-based lowering of testosterone (T). De-novo intra-tumoral steroid synthesis is a suggested biological mechanism of castration resistant PCa, but the
Hein Vincent Stroomberg, Anne Jørgensen, Klaus Brasso, John Erik Nielsen, Anders Juul, Hanne Frederiksen, Martin Blomberg Jensen, Martin Andreas Røder   +7 more
doaj   +1 more source

Impact of Tobacco Cigarette Smoking on Semen Quality and Serum Levels of Sex Hormones in Men: A Cross-Sectional Population-Based Study. [PDF]

Health Sci Rep
ABSTRACT Background and Aims The detrimental effect of tobacco cigarette smoking on human health has been reported in previous studies. The aim of the current study is to assess the effect of tobacco cigarette smoking on sperm quality and serum levels of sex hormones in men from the Jordanian population.
Al-Odat I, Al-Fawaeir S.
europepmc   +2 more sources

Short oestrous cycles in sheep during anoestrus involve defects in progesterone biosynthesis and luteal neovascularisation [PDF]

, 2014
Anoestrous ewes can be induced to ovulate by the socio-sexual, 'ram effect'. However, in some ewes the induced ovulation is followed by an abnormally short luteal phase causing a so called, "short cycle".
Acritopoulou, C Fabre Nys, Cahill, Chanvallon, Chemineau, Chemineau, Dickson, Dickson, H M Brown, Hazzard, Hinney, J Cognié, Koos, Land, Lassoued, Livak, Martin, Martin, Pearce, Pearce, Pritts, R J Scaramuzzi, Richards, Ungerfeld, Weems, Weems, Wulff, Wulff, Wulff   +28 more
core   +3 more sources

Inherited mutation of the luteinizing hormone/choriogonadotropin receptor (LHCGR) in empty follicle syndrome [PDF]

Fertility and Sterility, 2011
To test by genomic analysis whether empty follicle syndrome (EFS) in a family with two affected sisters has a genetic basis.Whole-exome sequencing in the context of clinical genetics.University hospital.Two women (36 and 32 years old at the time of the study) with EFS.Genetic counseling based on autosomal recessive inheritance.Discovery of a mutation ...
Kemal O. Yariz, Tom Walsh, Aslı Subasioglu Uzak, Michail Spiliopoulos, Duygu Duman, Göğşen Önalan, Mary‐Claire King, Mustafa Tekin   +7 more
openalex   +5 more sources

Functional Implications of LH/hCG Receptors in Pregnancy-Induced Cushing Syndrome [PDF]

, 2017
Context: Elevated human choriogonadotropin (hCG) may stimulate aberrantly expressed luteinizing hormone (LH)/hCG receptor (LHCGR) in adrenal glands, resulting in pregnancy-induced bilateral macronodular adrenal hyperplasia and transient Cushing syndrome (
Bertherat, Jerome, Blankenstein, Oliver, Chrusciel, Marcin, Doroszko, Milena, Hauptmann, Kathrin, Huhtaniemi, Ilpo, Kroiss, Matthias, Lacroix, André, Plöckinger, Ursula, Pöllinger, Alexander, Quinkler, Marcus, Radke, Cornelia, Rahman, Nafis, Saeger, Wolfgang, Steinmuller, Thomas, Tiling, Nikolaus, Weizsäcker, Katharina   +16 more
core   +1 more source

Acute hypoxia induced dysregulation of clock-controlled ovary functions

Frontiers in Physiology, 2022
High altitudes or exposure to hypoxia leads to female reproductive disorders. Circadian clocks are intrinsic time-tracking systems that enable organisms to adapt to the Earth’s 24-h light/dark cycle, which can be entrained by other environmental stimuli ...
Mengnan Ding, Yarong Lu, Yarong Lu, Xin Huang, Chen Xing, Shaojun Hou, Shaojun Hou, Shaojun Hou, Dongxue Wang, Dongxue Wang, Yifan Zhang, Wei Wang, Wei Wang, Chongchong Zhang, Chongchong Zhang, Min Zhang, Min Zhang, Fanfei Meng, Kun Liu, Guangchao Liu, Jincheng Zhao, Lun Song, Lun Song, Lun Song, Lun Song   +24 more
doaj   +1 more source

Transcriptional Changes in Cumulus Cells During In Vitro Maturation of Human Oocytes. [PDF]

Mol Reprod Dev
ABSTRACT This study assessed transcriptional changes in human cumulus cells (CCs) during oocyte maturation In Vitro. CCs were collected from 25 cumulus‐oocyte complexes derived from surplus ovarian medulla tissue of eight women (mean age 29 years, range 19–36) undergoing ovarian tissue cryopreservation without ovarian stimulation.
Cadenas J, Adrados CS, Kristensen SG, Macklon KT, Greve VH, Fedder J, Mamsen LS, Andersen CY.   +7 more
europepmc   +2 more sources