LHCGR (luteinizing hormone/choriogonadotropin receptor) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on LHCGR (luteinizing hormone/choriogonadotropin receptor), with data on DNA, on the protein encoded, and where the gene is implicated.
Tsai-Morris, CH, Dufau, ML
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Indian Journal of Endocrinology and Metabolism, 2021 Background: Polycystic ovarian syndrome (PCOS) is typically characterized by a spectrum of manifestations that include menstrual irregularities, anovulation, cysts, hyperandrogenic features like hirsutism, acne, alopecia, and various metabolic ...
Balaji Ramanathan +2 more
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The G-protein coupled estrogen receptor (GPER/GPR30) is a gonadotropin receptor dependent positive prognosticator in ovarian carcinoma patients. [PDF]
PLoS ONE, 2013 Follicle stimulating hormone receptor (FSHR) and luteinizing hormone receptor (LHCGR) were demonstrated to impact upon survival of patients suffering from epithelial ovarian cancer (EOC).
Sabine Heublein +6 more
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Impact of Neutral Sphingomyelinase Inhibition on Small Extracellular Vesicle Production by Mural Granulosa Cells and In Vitro Folliculogenesis in Mice. [PDF]
Mol Reprod DevABSTRACT Small extracellular vesicles (sEVs) function as critical regulators of ovarian follicular development. Although several pathways, including one involving neutral sphingomyelinase (nSMase), contribute to sEV production, the specific pathway active in ovarian follicles has not been clearly identified.
Matsushita K +7 more
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Significance of LHCGR polymorphisms in polycystic ovary syndrome: an association study
Scientific Reports, 2023 AbstractThis study was conducted to analyze the association of Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) gene rs4953616 and rs7371084 polymorphisms with the risk of polycystic ovary syndrome (PCOS) in Punjab, India. A total of 823 women (443 PCOS cases and 380 healthy controls) were enrolled in the present study.
Sukhjashanpreet Singh +3 more
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Scientific Reports, 2022 The human luteinising hormone choriogonadotropin receptor (LHCGR) is a G-protein coupled receptor activated by both human chorionic gonadotropin (hCG) and luteinizing hormone (LH), two structurally related gonadotropins with essential roles in ovulation ...
O. N. Mann +5 more
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Mutations in a novel, cryptic exon of the luteinizing hormone/chorionic gonadotropin receptor gene cause male pseudohermaphroditism. [PDF]
PLoS Medicine, 2008 Male pseudohermaphroditism, or Leydig cell hypoplasia (LCH), is an autosomal recessive disorder in individuals with a 46,XY karyotype, characterized by a predominantly female phenotype, a blind-ending vagina, absence of breast development, primary ...
Nina Kossack +4 more
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Diagnosis and treatment of familial male precocious puberty caused by LHCGR gene mutation: two case reports and literature review [PDF]
Zhenduanxue lilun yu shijian, 2022 Objective: To report the clinical features, gene detection results and treatment results of two patients with familial male limited precocious puberty(FMPP). Methods: Detailed medical history collection and physical examination were carried out in 2 FMPP
HE Qinyu, WANG Wei, CHEN Lifen, ZHANG Xuelei, DONG Zhiya
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BPA-Induced Deregulation of Epigenetic Patterns: Effects on Female Zebrafish Reproduction [PDF]
, 2016 Bisphenol A (BPA) is one of the commonest Endocrine Disruptor Compounds worldwide. It interferes with vertebrate reproduction, possibly by inducing deregulation of epigenetic mechanisms.
Carnevali, Oliana +6 more
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PLoS ONE, 2020 Prostate cancer (PCa) cells become castrate-resistant after initial tumor regression following castration-based lowering of testosterone (T). De-novo intra-tumoral steroid synthesis is a suggested biological mechanism of castration resistant PCa, but the
Hein Vincent Stroomberg +7 more
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