Results 21 to 30 of about 144,273 (312)

The End of Liberty [PDF]

SSRN Electronic Journal, 2021
Theorists treat liberty as a great equalizer. We can't easily distribute equal welfare, but we can purport to distribute equal liberty. In fact, however, nothing about "equal liberty" is meaningfully equal. To demonstrate, I turn not to familiar cases of distributing positive goods but to the distribution of a negative good, namely carceral punishment.
openaire   +2 more sources

COVID-19 related stress, quality of life, and intrinsic religiosity among college students during the global pandemic: A cross-sectional study

Cogent Psychology, 2023
The purpose of this correlational, cross-sectional design study was to examine the relationships between COVID-19-related stress, quality of life (QOL), and intrinsic religiosity of university students during the pandemic.
Rachel A. Joseph, Jichan J. Kim, Shanna W. Akers, Tracey Turner, Elizabeth Whorley, Kelly Lumpkin, Jenna Rosa, Catherine McElroy   +7 more
doaj   +1 more source

The use of resazurin as a novel antimicrobial agent against Francisella tularensis

Frontiers in Cellular and Infection Microbiology, 2013
The highly infectious and deadly pathogen, Francisella tularensis, is classified by the CDC as a Category A bioterrorism agent. Inhalation of a single bacterium results in an acute pneumonia with a 30-60% mortality rate without treatment.
Deanna Marie Schmitt, Dawn M O'Dee, Brianna N Cowan, James W.-M. Birch, Leanne K Mazzella, Gerard J Nau, Gerard J Nau, Joseph eHorzempa   +7 more
doaj   +1 more source

Identification of an N-terminal tag (580N) that improves the biosynthesis of fluorescent proteins in Francisella tularensis and other Gram-negative bacteria

Molecular and Cellular Probes
Utilization of fluorescent proteins is widespread for the study of microbial pathogenesis and host-pathogen interactions. Here, we discovered that linkage of the 36 N-terminal amino acids of FTL_0580 (a hypothetical protein of Francisella tularensis) to ...
Kristen Haggerty, Stuart Cantlay, Emily Young, Mariah K. Cashbaugh, Elio F. Delatore III, Rori Schreiber, Hayden Hess, Daniel R. Komlosi, Sarah Butler, Dalton Bolon, Theresa Evangelista, Takoda Hager, Claire Kelly, Katherine Phillips, Jada Voellinger, Robert M.Q. Shanks, Joseph Horzempa   +16 more
doaj   +1 more source

Antimicrobial activity of cefoperazone-sulbactam tested against Gram-Negative organisms from Europe, Asia-Pacific, and Latin America

International Journal of Infectious Diseases, 2020
Objectives: To evaluate the antimicrobial activities of cefoperazone-sulbactam and comparator agents tested against a large collection of clinical isolates of Gram-negative organisms. Methods: A total of 19 545 Gram-negative organisms were collected from
Helio S. Sader, Cecilia G. Carvalhaes, Jennifer M. Streit, Mariana Castanheira, Robert K. Flamm   +4 more
doaj   +1 more source

Tedizolid activity against a multicentre worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae recovered from patients with pneumonia (2017–2019)

International Journal of Infectious Diseases, 2021
Objectives: The antimicrobial activity of tedizolid and comparators was evaluated against a large worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae isolates recovered from patients with pneumonia.
Cecilia G. Carvalhaes, Helio S. Sader, Paul R. Rhomberg, Rodrigo E. Mendes   +3 more
doaj   +1 more source

Low Oxygen Concentration Reduces Neisseria gonorrhoeae Susceptibility to Resazurin

Antibiotics
Neisseria gonorrhoeae has developed resistance to every antibiotic currently approved for the treatment of gonorrhea, prompting the development of new therapies. The phenoxazine dye resazurin exhibits robust antimicrobial activity against N.
Justin Rice, Jordan Gibson, Emily Young, Kendall Souder, Kailee Cunningham, Deanna M. Schmitt   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Meropenem-Vaborbactam Activity against U.S. Multidrug-Resistant Enterobacterales Strains, Including Carbapenem-Resistant Isolates

Microbiology Spectrum, 2023
Carbapenems are a common first-line therapy for serious Gram-negative infections, but carbapenem-resistant Enterobacterales (CRE) isolates have become an urgent health concern. Klebsiella pneumoniae serine carbapenemases (KPCs) now have been disseminated
Dee Shortridge, Valerie Kantro, Mariana Castanheira   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source