Results 41 to 50 of about 9,387,974 (363)

Zweitveröffentlichungsservices an deutschen Universitätsbibliotheken: Leistungsspektrum, Kategorisierung und Einflussfaktoren

Library Ideas, 2022
Zweitveröffentlichungsservices sind an vielen Forschungseinrichtungen von zunehmender Bedeutung. In diesem Beitrag wird zunächst die Verbreitung der verschiedenen Dienstleistungen an Universitätsbibliotheken dargestellt und aufgezeigt, ob alle ...
Hannah Böhlke
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Zur Unmöglichkeit eines neutralen Bibliotheksangebots

Library Ideas, 2019
In der Diskussion um die Bereitstellung von Literatur rechter Verlage in Bibliotheken wird argumentiert, Bibliotheken seien zu weltanschaulicher Neutralität verpflichtet: „Prinzipiell unterliegen Bibliotheken, bei entsprechender Trägerschaft, als ...
Katharina Leyrer
doaj   +1 more source

Editorial #42: Das Leben, das Universum und der ganze Rest

Library Ideas, 2022
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Redaktion LIBREAS
doaj   +1 more source

Ultra-large library docking for discovering new chemotypes

Nature, 2019
Despite intense interest in expanding chemical space, libraries containing hundreds-of-millions to billions of diverse molecules have remained inaccessible. Here we investigate structure-based docking of 170 million make-on-demand compounds from 130 well-
Jiankun Lyu, Sheng Wang, T. E. Balius, I. Singh, A. Levit, Yurii S. Moroz, Matthew J. O’Meara, T. Che, Enkhjargal Algaa, Kateryna Tolmachova, A. Tolmachev, B. Shoichet, B. Roth, J. Irwin   +13 more
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Pure and Pseudo-pure Fluid Thermophysical Property Evaluation and the Open-Source Thermophysical Property Library CoolProp

Industrial & Engineering Chemistry Research, 2014
Over the last few decades, researchers have developed a number of empirical and theoretical models for the correlation and prediction of the thermophysical properties of pure fluids and mixtures treated as pseudo-pure fluids.
I. Bell, J. Wronski, S. Quoilin, V. Lemort   +3 more
semanticscholar   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

DEAL Open-Access-Option optimal nutzen – ein Bibliothekspraxisbericht

Library Ideas, 2020
Mit den DEAL-Verträgen steht das Versprechen im Raum, administrative und (autor*innenseitig) finanzielle Hürden für Open Access zu reduzieren. Für Bibliotheken bedeuten die DEAL-Verträge neben der Zentralisierung von Finanzströmen häufig auch mehr ...
Michaela Voigt
doaj   +1 more source

Performance Evaluation of The Center for Intellectual Development of Children and adolescents in Iran Using EFQM Model for Excellence and Suggested Model for Establishment of an International Children and Adolescent Library [PDF]

تحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2012
Objective: The present paper main objective is to evaluate the performance of CIDCA using EFQM model for excellence Methodology: A mixed method was used for the survey. Sample was drawn from CIDCA policy makers and senior management.
mina zakershahrak, Z Abazari
doaj   +1 more source