Results 91 to 100 of about 1,508,332 (327)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Linked Heritage Experience in Linking Heritage Information

open access: yesJLIS.it, 2013
The Linked Heritage Project started in April 2011. It is funded by the European Commission under the IST Policy Support Programme (ICT PSP), and runs for 30 months.
Gordon McKenna
doaj   +1 more source

Dynamic map display in library web OPAC [PDF]

open access: yes, 2007
Peer reviewedJournal ArticleAdding more features to the web OPAC or making the Integrated Library Management systems (ILMS) more compatible to external web services has been a tendency in recent years.

core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Schema di annotazione per la dottrina giuridica: il caso di studio della banca dati DoGi‑Dottrina Giuridica

open access: yesJLIS.it, 2013
Interoperability today is the key term for the enhancement of databases published on the web: the data, when isolated, have little value, on the contrary, their value increases significantly when different datasets, produced and published independently ...
Tommaso Agnoloni   +4 more
doaj   +1 more source

From many records to one graph: Heterogeneity conflicts in the Linked data restructuring cycle [PDF]

open access: yes, 2013
Introduction. During the last couple of years the library community has developed a number of comprehensive metadata standardization projects inspired by the idea of linked data, such as the BIBFRAME model.
Tallerås, Kim
core  

Telescope Bibliographies: an Essential Component of Archival Data Management and Operations

open access: yes, 2012
Assessing the impact of astronomical facilities rests upon an evaluation of the scientific discoveries which their data have enabled. Telescope bibliographies, which link data products with the literature, provide a way to use bibliometrics as an impact ...
Accomazzi, Alberto   +3 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

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