Results 81 to 90 of about 1,469,506 (316)

Modifications at the C-Terminus To Improve Pyrrole−Imidazole Polyamide Activity in Cell Culture [PDF]

open access: yes, 2009
Pyrrole−imidazole (Py-Im) hairpin polyamides are a class of small molecule DNA minor groove binding compounds that have been shown to modulate endogenous gene expression in cell culture.
Dervan, Peter B., Jacobs, Claire S.
core   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

LTS and Linked Data: a position paper [PDF]

open access: yes, 2015
"LTS and Linked Data: a position paper" outlines motivations for adopting linked data techniques for describing and managing our collections, and seeks to articulate a specific role for Library Technical Services (LTS) within this ...
Chew, Chiat Naun   +2 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Diffusion and adoption of Linked Data among libraries

open access: yesProceedings of the Association for Information Science and Technology, 2020
AbstractThrough content analyses of literature about the Linked Data (LD) adoption of individual libraries, this study found that the diffusion of LD among libraries is a decentralized process with high‐degree of reinvention and a continuous process that includes multiple stages and might last for many years.
openaire   +2 more sources

Linked Data at the Spanish National Library and the application of IFLA RDFS models [PDF]

open access: yes, 2011
The Spanish National Library (Biblioteca Nacional de España1. BNE) and the Ontology Engineering Group2 of Universidad Politécnica de Madrid are working on the joint project ?Preliminary Study of Linked Data?, whose aim is to enrich the Web of Data with ...
Escolano Rodríguez, Elena   +1 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Linking Library Metadata to the Web: the German Experiences

open access: yesJLIS.it, 2013
One of the major challenges of libraries today is to make metadata available for the usage and re-usage by researchers and the scientific community. Therefore it is necessary to open the cataloguing systems for non-restricted and completely free access.
Gabriele Meßmer
doaj   +6 more sources

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