Results 61 to 70 of about 1,659,781 (237)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Linear Hamiltonian Vector Fields on Lie Groups

Mathematics
Linear vector fields on Lie groups constitute a fundamental class of dynamical systems, as their flows are one-parameter subgroups of automorphisms and their infinitesimal behavior is entirely determined by derivations of the Lie algebra.
Víctor Ayala, María Luisa Torreblanca Todco   +1 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Quantum Field Tensor Model of Telecommunication Network Objects Interaction Based on Lie Groups

Proceedings of the International Conference on Applied Innovations in IT
This research explores the application of quantum physics methodologies to analyse digital flows within telecommunication networks. This study introduces a novel tensor model, grounded in the SU(2) Lie group, designed to simulate symmetric and asymmetric
Victor Tikhonov, Yevhen Vasiliu, Eduard Siemens, Oksana Vasylenko, Olena Tykhonova, Kateryna Shulakova, Olexandr Demchenko   +6 more
doaj   +1 more source

Hilbert-Haar coordinates and Miranda's theorem in Lie groups

Bruno Pini Mathematical Analysis Seminar, 2020
We study the interior regularity of solutions to a class of quasilinear equations of non-degenerate p-Laplacian type on Lie groups that admit a system of Hilbert-Haar coordinates. These are coordinates with respect to which every linear function has zero
András Domokos, Juan J. Manfredi
doaj   +1 more source

Regularity of Lie Groups

, 2018
We solve the regularity problem for Milnor's infinite dimensional Lie groups in the $C^0$-topological context, and provide necessary and sufficient regularity conditions for the standard setting ($C^k$-topology).
Hanusch, Maximilian
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Variations on the theme Euler angles [PDF]

Surveys in Mathematics and its Applications, 2019
We discuss different parameterizations of the Lie group SO(3). The well-known Rodrigues formula describes the three dimensional orthogonal matrices in terms of their axes and angles of rotation.
Clementina D. Mladenova, Ivaïlo M. Mladenov   +1 more
doaj  

The Pilgerschritt (Liedl) transform

ESAIM: Proceedings and Surveys, 2014
The Pilgerschritt transform was introduced by Roman Liedl, Innsbruck, in the late seventies of the last century. He came up with the idea for this transform after studies of the Volterra product integral and dealing with questions in ...
Förg-Rob Wolfgang
doaj   +1 more source