Results 71 to 80 of about 1,251,284 (265)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
AgricultureSugarcane is the most important cash crop for producing sugar and the most promising high-yield bioenergy crop in China. Lai-bin is a major sugarcane growing and karst area in the Guangxi Province of China.
Yunchuan Yang +7 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Cocoa farmers' characteristics on climate variability and its effects on climate change adaptation strategy [PDF]
Global Journal of Environmental Science and ManagementBACKGROUND AND OBJECTIVES: Climate change has a greater influence on agriculture through local climate variability than global climate patterns. The impact of climate change on agricultural productivity and shifts in crop patterns varies significantly ...
I. Idawati +6 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
BatteriesCylindrical lithium-ion batteries are widely used in consumer electronics, electric vehicles, and energy storage applications. However, safety risks due to thermal runaway-induced fire and explosions have prompted the need for safety analysis ...
Sahithi Maddipatla +2 more
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The Use of UL 1642 Impact Testing for Li-ion Pouch Cells
IEEE Access, 2019 The industry demand for high-capacity cells with a small footprint is a result of demands for improved products and new applications. However, this presents challenges in terms of safety.
Ryan Aalund, Michael Pecht
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
SensorsUnderstanding and predicting the behaviour of fatigue cracks are essential for ensuring safety, optimising maintenance strategies, and extending the lifespan of critical components in industries such as aerospace, automotive, civil engineering and energy.
Hilal Doğanay Katı +4 more
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