Clonal dynamics of haematopoiesis across the human lifespan
Age-related change in human haematopoiesis causes reduced regenerative capacity1, cytopenias2, immune dysfunction3 and increased risk of blood cancer4–6, but the reason for such abrupt functional decline after 70 years of age remains unclear.
E. Mitchell+28 more
semanticscholar +1 more source
Perceptual Learning: Changes across the Lifespan [PDF]
New research reveals a complex interaction between attention and learning across the lifespan. In young adults, attention guides learning. In older adults, attention declines lead to less selective learning. Counterintuitively, however, in children better attention relates to less selective learning.
openaire +3 more sources
It is my pleasure to present the second issue of the second volume of Lifespans & Styles: Undergraduate Working Papers on Intraspeaker Variation. This issue includes six papers from nine authors. The first three papers are by undergraduate students in Dr
Lauren Hall-Lew
doaj +3 more sources
rDNA array length is a major determinant of replicative lifespan in budding yeast
Significance Genes encoding ribosomal RNA (rDNA) are organized into a repetitive array in eukaryotic genomes. The copy number of these genes often varies and is responsive to genetics and environment.
Manuel Hotz+5 more
semanticscholar +1 more source
Local structure-function relationships in human brain networks across the lifespan
A growing number of studies have used stylized network models of communication to predict brain function from structure. Most have focused on a small set of models applied globally.
Farnaz Zamani Esfahlani+4 more
semanticscholar +1 more source
A naturally occurring polymorphism at Drosophila melanogaster Lim3 Locus, a homolog of human LHX3/4, affects Lim3 transcription and fly lifespan. [PDF]
Lim3 encodes an RNA polymerase II transcription factor with a key role in neuron specification. It was also identified as a candidate gene that affects lifespan.
Olga Yu Rybina, Elena G Pasyukova
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A patch in time saves nine: Methods for the identification of localised dynamical behaviour and lifespans of coherent structures [PDF]
We develop a transfer operator-based method for the detection of coherent structures and their associated lifespans. Characterising the lifespan of coherent structures allows us to identify dynamically meaningful time windows, which may be associated with transient coherent structures in the localised phase space, as well as with time intervals within ...
arxiv +1 more source
Creativity across the lifespan: changes with age and with dementia
Abstract Background It is well known that older age is associated with losses in cognitive functioning. Less is known about the extent to which creativity is changing with age or dementia. Aim of the current study was to gain more insights into psychometric aspects of creativity in younger and older people as well as ...
Ross, Sabrina D+4 more
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Goin’ Home: The Role of Vowel Raising in Indexing an Ethnic Identity
Vowel height can be seen as a feature indexing a particular ethnic identity or indicating a style shift between two such identities. This paper focuses on Bradford-born South Asian musician Zayn Malik, an interesting subject given his prominent status as
Suzey Ingold
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Variable pathogenicity determines individual lifespan in Caenorhabditis elegans. [PDF]
A common property of aging in all animals is that chronologically and genetically identical individuals age at different rates. To unveil mechanisms that influence aging variability, we identified markers of remaining lifespan for Caenorhabditis elegans.
Adolfo Sánchez-Blanco, Stuart K Kim
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