Results 71 to 80 of about 14,125,984 (386)
A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia
eLife, 2017 The genetic mechanisms regulating the brain and behaviour across the lifespan are poorly understood. We found that lifespan transcriptome trajectories describe a calendar of gene regulatory events in the brain of humans and mice.
Nathan G Skene +2 more
doaj +1 more source
Brain Tissue Segmentation Across the Human Lifespan via Supervised Contrastive Learning [PDF]
arXiv, 2023 Automatic segmentation of brain MR images into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) is critical for tissue volumetric analysis and cortical surface reconstruction. Due to dramatic structural and appearance changes associated with developmental and aging processes, existing brain tissue segmentation methods are only viable ...
arxiv
Sex differences in intimate relationships [PDF]
Sci. Rep. 2, 370 (2012), 2012 Social networks have turned out to be of fundamental importance both for our understanding human sociality and for the design of digital communication technology. However, social networks are themselves based on dyadic relationships and we have little understanding of the dynamics of close relationships and how these change over time.
arxiv +1 more source
Quantifying the structure of free association networks across the lifespan [PDF]
, 2017 We investigate how the mental lexicon changes over the lifespan using free association data from over 8,000 individuals, ranging from 10 to 84 years of age, with more than 400 cue words per age group. Using network analysis, with words as nodes and edges
De Deyne, S., Dubossarsky, H., Hills, T.
core +1 more source
Gene expression defines natural changes in mammalian lifespan [PDF]
Aging Cell, 2015 SummaryMammals differ more than 100‐fold in maximum lifespan, which can be altered in either direction during evolution, but the molecular basis for natural changes in longevity is not understood. Divergent evolution of mammals also led to extensive changes in gene expression within and between lineages.
Sang-Goo Lee +15 more
openaire +4 more sources
Individual and group level personality change across the lifespan in dogs
Scientific Reports, 2020 In humans, age-related changes in personality occur in a non-random fashion with respect to their direction, timing, and magnitude. In dogs, there are still gaps in our knowledge about the detailed dynamics of age-related personality changes. We analysed
Borbála Turcsán +5 more
doaj +1 more source
Susceptible-infected-susceptible model on networks with eigenvector localization [PDF]
Physical Review E 101, 042310 (2020), 2017 It is a longstanding debate on the absence of threshold for susceptible-infected-susceptible (SIS) model on networks with finite second order moment of degree distribution. The eigenvector localization of the adjacency matrix for a network gives rise to the inactive Griffiths phase featuring slow decay of the activity localized around highly connected ...
arxiv +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
An In Silico Model to Simulate the Evolution of Biological Aging
, 2016 Biological aging is characterized by an age-dependent increase in the probability of death and by a decrease in the reproductive capacity. Individual age-dependent rates of survival and reproduction have a strong impact on population dynamics, and the ...
Valenzano, Dario Riccardo +1 more
core +1 more source
Personality trait stability and change
Personality Science, 2021 Personality traits continue to change throughout the lifespan. However, we still know little about when, why, and how personality traits change. In this paper, we review the current state of scientific evidence regarding the nature, sources, and ...
W. Bleidorn +14 more
semanticscholar +1 more source