Results 81 to 90 of about 162,248 (302)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A High Definition Study of Syntactic Lifespan Change [PDF]
, 2018 We examine variable use of Stylistic Fronting (SF) in Icelandic in thousands of parliament speeches given by parliament member Steingrímur J. Sigfússon between 1990-2013.
Stefánsdóttir, Lilja Björk +1 more
core +1 more source
The urge to unmerge: a case of structural change across the lifespan [PDF]
, 2023 This paper considers change across the lifespan by investigating an adult speaker’s development from a one-part low back vowel system to a two-part system.
Hellyer, RJ +3 more
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Lifespan perspectives on psychological contracts [PDF]
, 2017 This chapter discusses the role of psychological contracts along the lifespan and careers of workers. It explains the meaning of the psychological contract, and discusses lifespan theories in relation to how psychological contracts may change with age ...
Matthijs Bal (17153377) +1 more
core +2 more sources
Genome Biology, 2018 Background Mammalian species exhibit a wide range of lifespans. To date, a robust and dynamic molecular readout of these lifespan differences has not yet been identified.
Robert Lowe +13 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Genome Biology, 2017 Background Global but predictable changes impact the DNA methylome as we age, acting as a type of molecular clock. This clock can be hastened by conditions that decrease lifespan, raising the question of whether it can also be slowed, for example, by ...
Tina Wang +9 more
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Handedness throughout the lifespan: Cross-sectional view on sex differences as asymmetries change
Frontiers in Psychology, 2015 Manual asymmetries has been studied by many researchers, however contradictory findings still exist as to whether preferred manual asymmetries increases with age or do we become more ambidextrous.
Mukundhan eSivagnanasunderam +5 more
doaj +1 more source