Results 11 to 20 of about 860,212 (198)
Aryl Hydrocarbon Receptor as an Anticancer Target: An Overview of Ten Years Odyssey
Molecules, 2023 Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor belonging to the basic helix–loop–helix (bHLH)/per-Arnt-sim (PAS) superfamily, is traditionally known to mediate xenobiotic metabolism.
Hamza Hanieh +4 more
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Preparation and determination number of new ZN (II) complexes with a combination of ligands, studying the effect of laser and evaluating their activity on bacterial swabs [PDF]
مجلة التربية والعلم, 2018 Acetylacetoneazineoxime {AAOH}, acetylacetoneazinebis(oxime) {AABOH2}, benzilsemicarbazone {BScH} and benzilsemicarbazone-hydrazone {BScZH} have been prepared using classical, one pot and microwave heating methods followed by the preparation of new zinc(
Awos Alezi, Zhour Altaee
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Advances on Mrgprs itch receptors and their ligands
Pifu-xingbing zhenliaoxue zazhi, 2023 Although histamine is an important physiologically active substance in pruritus,antihistamine drugs can only relieve a small proportion of symptoms in chronic pruritus.
Jing HU, Zhijian CAO
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Drug Delivery, 2022 The systemic drug has historically been preferred for the treatment of the majority of pathological conditions, particularly liver cancer. Indeed, this mode of treatment is associated with adverse reactions, toxicity, off-target accumulation, and rapid ...
Jianyong Ma +6 more
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Aptamer-Based Technologies in Foodborne Pathogen Detection
Frontiers in Microbiology, 2016 Aptamers are single stranded DNA or RNA ligands, which can be selected by a method called systematic evolution of ligands by exponential enrichment (SELEX); and they can specifically recognize and bind to their targets.
Jun Teng +7 more
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Towards Water Soluble Mitochondria-Targeting Theranostic Osmium(II) Triazole-Based Complexes
Molecules, 2016 The complex [Os(btzpy)2][PF6]2 (1, btzpy = 2,6-bis(1-phenyl-1,2,3-triazol-4-yl)pyridine) has been prepared and characterised. Complex 1 exhibits phosphorescence (λem = 595 nm, τ = 937 ns, φem = 9.3% in degassed acetonitrile) in contrast to its known ...
Salem A. E. Omar +5 more
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Galanin Receptors and Ligands [PDF]
Frontiers in Endocrinology, 2012 The neuropeptide galanin was first discovered 30 years ago. Today, the galanin family consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide (GMAP), and alarin and this family has been shown to be involved in a wide variety of biological and pathological functions.
Webling, Kristin E. B. +3 more
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CAT-Site: Predicting Protein Binding Sites Using a Convolutional Neural Network
Pharmaceutics, 2022 Identifying binding sites on the protein surface is an important part of computer-assisted drug design processes. Reliable prediction of binding sites not only assists with docking algorithms, but it can also explain the possible side-effects of a ...
Žan Hafner Petrovski +2 more
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Frontiers in Molecular Neuroscience, 2018 C-to-U RNA editing of glycine receptors (GlyR) can play an important role in disease progression of temporal lobe epilepsy (TLE) as it may contribute in a neuron type-specific way to neuropsychiatric symptoms of the disease.
Svenja Kankowski +8 more
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Crystallographic study of PET radiotracers in clinical evaluation for early diagnosis of Alzheimers
Acta Crystallographica Section E, 2014 The title compound, C24H25NO3·2CH3OH, which crystallized as a methanol disolvate, has applications as a PET radiotracer in the early diagnosis of Alzheimer's disease.
Angela Altomare +6 more
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