Results 11 to 20 of about 2,296,826 (424)
Spontaneous Patterning of Binary Ligand Mixtures on CdSe Nanocrystals: from Random to Janus Packing [PDF]
ACS Nano, (2023) 17(6) 5852-5860, 2023 Binary compositions of surface ligands are known to improve the colloidal stability and fluorescence quantum yield of nanocrystals (NCs), due to ligand-ligand interactions and surface organization. Herein, we follow the thermodynamics of a ligand exchange reaction of CdSe NCs with alkylthiols mixtures.
arxiv +1 more source
Annotation of biologically relevant ligands in UniProtKB using ChEBI
bioRxiv, 2022 Motivation To provide high quality, computationally tractable annotation of binding sites for biologically relevant (cognate) ligands in UniProtKB using the chemical ontology ChEBI (Chemical Entities of Biological Interest), to better support efforts to ...
E. Coudert +8 more
semanticscholar +1 more source
Ligand-induced protein dynamics differences correlate with protein-ligand binding affinities: An unsupervised deep learning approach [PDF]
Commun. Biol. 5, 481 (2022), 2021 Prediction of protein-ligand binding affinity is a major goal in drug discovery. Generally, free energy gap is calculated between two states (e.g., ligand binding and unbinding). The energy gap implicitly includes the effects of changes in protein dynamics induced by the binding ligand.
arxiv +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 Objective To investigate the anti⁃tumoral effect of ACT001, a novel antitumor compound, on the nuclear factor⁃κB (NF⁃κB) pathway and programmed cell death protein ligand 1 (PDL1) expression in U87 glioblastoma cell line.
ZHANG Jin⁃hao +9 more
doaj +1 more source
Frontiers in Endocrinology, 2023 IntroductionNR5A1 and NR5A2 belong to an orphan nuclear receptor group, and approximately 60% of their amino acid sequences are conserved. Transcriptional regulation of NR5A receptors depends on interactions with co-factors or unidentified ligands ...
Maki Gau +9 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Small interfering RNA (siRNA)-mediated mRNA degradation approach have imparted its eminence against several difficult-to-treat genetic disorders and other allied diseases.
Rushikesh Fopase +6 more
doaj +1 more source
Preparation and determination number of new ZN (II) complexes with a combination of ligands, studying the effect of laser and evaluating their activity on bacterial swabs [PDF]
مجلة التربية والعلم, 2018 Acetylacetoneazineoxime {AAOH}, acetylacetoneazinebis(oxime) {AABOH2}, benzilsemicarbazone {BScH} and benzilsemicarbazone-hydrazone {BScZH} have been prepared using classical, one pot and microwave heating methods followed by the preparation of new zinc(
Awos Alezi, Zhour Altaee
doaj +1 more source
Estimating tissue-specific peptide abundance from public RNA-Seq data
Frontiers in Genetics, 2023 Several novel MHC class I epitope prediction tools additionally incorporate the abundance levels of the peptides’ source antigens and have shown improved performance for predicting immunogenicity.
Angela Frentzen +5 more
doaj +1 more source
Frontiers in Immunology, 2020 The ubiquitously expressed, monomorphic MHC class Ib molecule MHC class I-related protein 1 (MR1) presents microbial metabolites to mucosal-associated invariant T (MAIT) cells.
Corinna Kulicke +10 more
doaj +1 more source
Inhibitory Immune Checkpoint Receptors and Ligands as Prognostic Biomarkers in COVID-19 Patients
Frontiers in Immunology, 2022 Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2. During T-cell activation, the immune system uses different checkpoint pathways to maintain co-inhibitory and co-stimulatory signals.
Mohammad A. Al-Mterin +3 more
doaj +1 more source