Annotation of biologically relevant ligands in UniProtKB using ChEBI
Motivation To provide high quality, computationally tractable annotation of binding sites for biologically relevant (cognate) ligands in UniProtKB using the chemical ontology ChEBI (Chemical Entities of Biological Interest), to better support efforts to ...
E. Coudert +8 more
semanticscholar +1 more source
The ubiquitously expressed, monomorphic MHC class Ib molecule MHC class I-related protein 1 (MR1) presents microbial metabolites to mucosal-associated invariant T (MAIT) cells.
Corinna Kulicke +10 more
doaj +1 more source
Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands [PDF]
A diverse library of cationic silver complexes bearing bis(N-heterocyclic carbene) ligands have been prepared which exhibit cytotoxicity comparable to cisplatin against the adenocarcinomas MCF7 and DLD1.
Baker +32 more
core +1 more source
Experimental and theoretical investigation of ligand effects on the synthesis of ZnO nanoparticles [PDF]
ZnO nanoparticles with highly controllable particle sizes(less than 10 nm) were synthesized using organic capping ligands in Zn(Ac)2 ethanolic solution.
A Dev +68 more
core +3 more sources
IntroductionNR5A1 and NR5A2 belong to an orphan nuclear receptor group, and approximately 60% of their amino acid sequences are conserved. Transcriptional regulation of NR5A receptors depends on interactions with co-factors or unidentified ligands ...
Maki Gau +9 more
doaj +1 more source
Aryl Hydrocarbon Receptor as an Anticancer Target: An Overview of Ten Years Odyssey
Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor belonging to the basic helix–loop–helix (bHLH)/per-Arnt-sim (PAS) superfamily, is traditionally known to mediate xenobiotic metabolism.
Hamza Hanieh +4 more
doaj +1 more source
Preparation and determination number of new ZN (II) complexes with a combination of ligands, studying the effect of laser and evaluating their activity on bacterial swabs [PDF]
Acetylacetoneazineoxime {AAOH}, acetylacetoneazinebis(oxime) {AABOH2}, benzilsemicarbazone {BScH} and benzilsemicarbazone-hydrazone {BScZH} have been prepared using classical, one pot and microwave heating methods followed by the preparation of new zinc(
Awos Alezi, Zhour Altaee
doaj +1 more source
Advances on Mrgprs itch receptors and their ligands
Although histamine is an important physiologically active substance in pruritus,antihistamine drugs can only relieve a small proportion of symptoms in chronic pruritus.
Jing HU, Zhijian CAO
doaj +1 more source
Crystal engineering with 2,2':6',2"- terpyridine derivatives and their metal complexes : from simple building blocks to coordination polymers and networks [PDF]
This thesis concerns the design of ligands for use in the construction of larger supramolecular systems, with emphasis on the application of 4'-substitured 2,2',6',2''- terpyridine ligands and their iron(II) and ruthenium(II) complexes in crystal ...
Beves, Jonathon Edward
core +1 more source
Electrochemistry of ferrocenylphosphines FcCH₂PR₂ (Fc=(η⁵-C₅H₅)Fe(η⁵-C₅H₄); R=Ph, CH₂OH and CH₂CH₂CN), and some phosphine oxide, phosphine sulfide, phosphonium and metal complex derivatives [PDF]
Electrochemical studies of the free ferrocenylphosphine ligands FcCH₂PR₂ (Fc=(η⁵-C₅H₅)Fe(η⁵-C₅H₄); R=Ph, CH₂OH and CH₂CH₂CN) and some phosphine oxide, phosphine sulfide, phosphonium and metal derivatives are described.
Downard, Alison J. +2 more
core +2 more sources

