Results 11 to 20 of about 1,301,268 (279)
Ligand‐dependent ribozymes [PDF]
WIREs RNA, 2016 The discovery of catalytic RNA (ribozymes) more than 30 years ago significantly widened the horizon of RNA‐based functions in natural systems. Similarly to the activity of protein enzymes that are often modulated by the presence of an interaction partner, some examples of naturally occurring ribozymes are influenced by ligands that can either act as ...
Felletti, Michele, Hartig, Jörg S.
openaire +3 more sources
NKG2D and its ligands: one for all, all for one [PDF]
, 2018 The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal cells but can be induced on damaged, transformed or infected cells, with ...
Cerboni, Cristina +7 more
core +2 more sources
Frontiers in Endocrinology, 2023 IntroductionNR5A1 and NR5A2 belong to an orphan nuclear receptor group, and approximately 60% of their amino acid sequences are conserved. Transcriptional regulation of NR5A receptors depends on interactions with co-factors or unidentified ligands ...
Maki Gau +9 more
doaj +1 more source
Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands [PDF]
, 2012 A diverse library of cationic silver complexes bearing bis(N-heterocyclic carbene) ligands have been prepared which exhibit cytotoxicity comparable to cisplatin against the adenocarcinomas MCF7 and DLD1.
Baker +32 more
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Aryl Hydrocarbon Receptor as an Anticancer Target: An Overview of Ten Years Odyssey
Molecules, 2023 Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor belonging to the basic helix–loop–helix (bHLH)/per-Arnt-sim (PAS) superfamily, is traditionally known to mediate xenobiotic metabolism.
Hamza Hanieh +4 more
doaj +1 more source
Experimental and theoretical investigation of ligand effects on the synthesis of ZnO nanoparticles [PDF]
, 2012 ZnO nanoparticles with highly controllable particle sizes(less than 10 nm) were synthesized using organic capping ligands in Zn(Ac)2 ethanolic solution.
A Dev +68 more
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Advances on Mrgprs itch receptors and their ligands
Pifu-xingbing zhenliaoxue zazhi, 2023 Although histamine is an important physiologically active substance in pruritus,antihistamine drugs can only relieve a small proportion of symptoms in chronic pruritus.
Jing HU, Zhijian CAO
doaj +1 more source
RAGE Signaling in Skeletal Biology [PDF]
, 2019 PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M. +2 more
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Crystal engineering with 2,2':6',2"- terpyridine derivatives and their metal complexes : from simple building blocks to coordination polymers and networks [PDF]
, 2008 This thesis concerns the design of ligands for use in the construction of larger supramolecular systems, with emphasis on the application of 4'-substitured 2,2',6',2''- terpyridine ligands and their iron(II) and ruthenium(II) complexes in crystal ...
Beves, Jonathon Edward
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TMEM97 and PGRMC1 do not mediate sigma-2 ligand-induced cell death [PDF]
, 2019 Sigma-2 receptors have been implicated in both tumor proliferation and neurodegenerative diseases. Recently the sigma-2 receptor was identified as transmembrane protein 97 (TMEM97).
Hawkins, William G. +9 more
core +3 more sources