Aptamer-Based Technologies in Foodborne Pathogen Detection
Aptamers are single stranded DNA or RNA ligands, which can be selected by a method called systematic evolution of ligands by exponential enrichment (SELEX); and they can specifically recognize and bind to their targets.
Jun Teng +7 more
doaj +1 more source
CAT-Site: Predicting Protein Binding Sites Using a Convolutional Neural Network
Identifying binding sites on the protein surface is an important part of computer-assisted drug design processes. Reliable prediction of binding sites not only assists with docking algorithms, but it can also explain the possible side-effects of a ...
Žan Hafner Petrovski +2 more
doaj +1 more source
The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs [PDF]
G protein coupled receptors (GPCRs) are the most historically successful therapeutic targets. Despite this success there are many important aspects of GPCR pharmacology and function that have yet to be exploited to their full therapeutic potential.
Hudson, Brian D. +2 more
core +1 more source
Towards Water Soluble Mitochondria-Targeting Theranostic Osmium(II) Triazole-Based Complexes
The complex [Os(btzpy)2][PF6]2 (1, btzpy = 2,6-bis(1-phenyl-1,2,3-triazol-4-yl)pyridine) has been prepared and characterised. Complex 1 exhibits phosphorescence (λem = 595 nm, τ = 937 ns, φem = 9.3% in degassed acetonitrile) in contrast to its known ...
Salem A. E. Omar +5 more
doaj +1 more source
Electrochemistry of ferrocenylphosphines FcCH₂PR₂ (Fc=(η⁵-C₅H₅)Fe(η⁵-C₅H₄); R=Ph, CH₂OH and CH₂CH₂CN), and some phosphine oxide, phosphine sulfide, phosphonium and metal complex derivatives [PDF]
Electrochemical studies of the free ferrocenylphosphine ligands FcCH₂PR₂ (Fc=(η⁵-C₅H₅)Fe(η⁵-C₅H₄); R=Ph, CH₂OH and CH₂CH₂CN) and some phosphine oxide, phosphine sulfide, phosphonium and metal derivatives are described.
Downard, Alison J. +2 more
core +2 more sources
Ligand design for site-selective installation of Pd and Pt centers to generate homo- and heteropolymetallic motifs [PDF]
The modular synthesis of a series of nitrogen-rich polydentate ligands that feature a common pincer-type framework is reported. These ligands allow for site-selective installation of palladium and platinum to give rise to bi- and trimetallic complexes ...
Peters, Jonas C., Suess, Daniel L. M.
core +2 more sources
C-to-U RNA editing of glycine receptors (GlyR) can play an important role in disease progression of temporal lobe epilepsy (TLE) as it may contribute in a neuron type-specific way to neuropsychiatric symptoms of the disease.
Svenja Kankowski +8 more
doaj +1 more source
Mercury(II) complexes (Me-maloNHCDipp)HgCl (1b), (t-Bu-maloNHCDipp)HgCl (2b) and (t-Bu-maloNHCDipp)HgMe (2c) supported by anionic N-heterocyclic carbenes have been obtained in good yields from the reaction of the potassium salt of N-heterocyclic carbene ...
Chandrakanta Dash +2 more
doaj +1 more source
The lipocalin beta-lactoglobulin (BLG) is a major protein compound in cow’s milk, and we detected it in cattle stable dust. BLG may be a novel player in the farm protective effect against atopic sensitization and hayfever.
Sheriene Moussa Afify +12 more
doaj +1 more source
Bis[μ-bis(diphenylphosphino)methane-К²P:P’]bis[(saccharinato-КN)- palladium(I)] dichloromethane solvate [PDF]
The dimeric palladium(I) saccharinate complex [Pd₂(sac)₂(dppm)₂], has been characterized as its di¬chloro¬methane solvate, i.e. [Pd₂(C₇H₄NO₃S)₂(C₂₅H₂₂P₂)₂]•CH₂Cl₂.
Chung, Dong C. +2 more
core +2 more sources

