Results 21 to 30 of about 2,433,325 (381)
Aptamer-Based Technologies in Foodborne Pathogen Detection
Frontiers in Microbiology, 2016 Aptamers are single stranded DNA or RNA ligands, which can be selected by a method called systematic evolution of ligands by exponential enrichment (SELEX); and they can specifically recognize and bind to their targets.
Jun Teng +7 more
doaj +1 more source
RAGE Signaling in Skeletal Biology [PDF]
, 2019 PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M. +2 more
core +1 more source
Towards Water Soluble Mitochondria-Targeting Theranostic Osmium(II) Triazole-Based Complexes
Molecules, 2016 The complex [Os(btzpy)2][PF6]2 (1, btzpy = 2,6-bis(1-phenyl-1,2,3-triazol-4-yl)pyridine) has been prepared and characterised. Complex 1 exhibits phosphorescence (λem = 595 nm, τ = 937 ns, φem = 9.3% in degassed acetonitrile) in contrast to its known ...
Salem A. E. Omar +5 more
doaj +1 more source
CAT-Site: Predicting Protein Binding Sites Using a Convolutional Neural Network
Pharmaceutics, 2022 Identifying binding sites on the protein surface is an important part of computer-assisted drug design processes. Reliable prediction of binding sites not only assists with docking algorithms, but it can also explain the possible side-effects of a ...
Žan Hafner Petrovski +2 more
doaj +1 more source
The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs [PDF]
, 2013 G protein coupled receptors (GPCRs) are the most historically successful therapeutic targets. Despite this success there are many important aspects of GPCR pharmacology and function that have yet to be exploited to their full therapeutic potential.
Hudson, Brian D. +2 more
core +1 more source
Metal–ligand cooperation at tethered π-ligands
Dalton Transactions, 2016 Recent advances in the use of tethered π-coordinating ligands for metal–ligand cooperation.
Dide G. A. Verhoeven, Marc-Etienne Moret
openaire +4 more sources
The Role of Ligands in the Chemical Synthesis and Applications of Inorganic Nanoparticles.
Chemical Reviews, 2019 The design of nanoparticles is critical for their efficient use in many applications ranging from biomedicine to sensing and energy. While shape and size are responsible for the properties of the inorganic nanoparticle core, the choice of ligands is of ...
Amelie Heuer-Jungemann +15 more
semanticscholar +1 more source
Frontiers in Molecular Neuroscience, 2018 C-to-U RNA editing of glycine receptors (GlyR) can play an important role in disease progression of temporal lobe epilepsy (TLE) as it may contribute in a neuron type-specific way to neuropsychiatric symptoms of the disease.
Svenja Kankowski +8 more
doaj +1 more source
TMEM97 and PGRMC1 do not mediate sigma-2 ligand-induced cell death [PDF]
, 2019 Sigma-2 receptors have been implicated in both tumor proliferation and neurodegenerative diseases. Recently the sigma-2 receptor was identified as transmembrane protein 97 (TMEM97).
Hawkins, William G. +9 more
core +3 more sources
LigParGen web server: an automatic OPLS-AA parameter generator for organic ligands
Nucleic Acids Res., 2017 The accurate calculation of protein/nucleic acid–ligand interactions or condensed phase properties by force field-based methods require a precise description of the energetics of intermolecular interactions.
Leela S. Dodda +3 more
semanticscholar +1 more source