Results 351 to 360 of about 2,378,379 (395)
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The Selectins and Their Ligands

1993
Among the four major groups of cell adhesion molecules (CAMs) the selectins represent the smallest and most recently identified gene family (Lasky 1992; Vestweber 1992). In contrast to the three large families of the integrins, the immunoglobulin super gene family and the cadherins, the selectins consist of only three members: L-, E-, and P-selectin ...
openaire   +3 more sources

Searching for peptide ligands with an epitope library.

Science, 1990
Tens of millions of short peptides can be easily surveyed for tight binding to an antibody, receptor or other binding protein using an "epitope library." The library is a vast mixture of filamentous phage clones, each displaying one peptide sequence on ...
J. Scott, George P Smith
semanticscholar   +1 more source

Origin of the Substitution Mechanism for the Binding of Organic Ligands on the Surface of CsPbBr3 Perovskite Nanocubes.

Journal of Physical Chemistry Letters, 2017
Optoelectronic properties of CsPbBr3 perovskite nanocubes (NCs) depend strongly on the interaction of the organic passivating molecules with the inorganic crystal.
V. K. Ravi   +7 more
semanticscholar   +1 more source

Cannabinergic ligands

Chemistry and Physics of Lipids, 2002
The understanding of the pharmacology surrounding the cannabinergic system has seen many advances since the discovery of the CB1 receptor in the mammalian brain and the CB2 receptor in the periphery. Among these advances is the discovery of the endogenous ligands arachidonoylethanolamide (anandamide) and 2-arachidonoylglycerol amide (2-AG), which are ...
Sonya L, Palmer   +2 more
openaire   +2 more sources

A Ligand, Not a Carrier [PDF]

open access: possibleScience, 2008
Volatile odorants are generally thought to bind to G protein-coupled receptors and thereby activate a downstream signaling pathway, a paradigm challenged by data from Laughlin et al . In Drosophila , various odorant-binding proteins are secreted into the lymph around subsets of olfactory ...
openaire   +2 more sources

New chiral phosphorus ligands for enantioselective hydrogenation.

Chemical Reviews, 2003
The increasing demand to produce enantiomerically pure pharmaceuticals, agrochemicals, flavors, and other fine chemicals has advanced the field of asymmetric catalytic technologies.1,2 Among all asymmetric catalytic methods, asymmetric hydrogenation ...
Wenjun Tang, Xumu Zhang
semanticscholar   +1 more source

Integrins and Their Ligands

1993
Integrins are expressed on almost every cell type and are responsible for the linkage of the extracellular matrix with the cytoskeleton. In this review I have focused on the intra- and extracellular proteins that bind to integrins. Although many integrins bind to the same extracellular ligand, they mostly recognize different sites on these ligands ...
openaire   +3 more sources

Nuclear-Receptor Ligands and Ligand-Binding Domains

Annual Review of Biochemistry, 1999
▪ Abstract  The determination of several structures of nuclear receptor ligand binding domains (LBD) has led to new insights into the mechanism of action of this very important class of receptors. This review describes and compares the different LBD structures and their relationship to the function of the nuclear receptors.
R V, Weatherman   +2 more
openaire   +2 more sources

ProPose: Steered Virtual Screening by Simultaneous Protein—Ligand Docking and Ligand—Ligand Alignment. [PDF]

open access: possibleChemInform, 2005
The 'model-free' screening engine ProPose implements a general method for performing simultaneous protein-ligand docking, ligand-ligand alignment, pharmacophore queries-and combinations thereof-in order to incorporate a priori information into screening protocols.
openaire   +3 more sources

[23] Protein-ligand interactions: Exchange processes and determination of ligand conformation and protein-ligand contacts

1994
Publisher Summary This chapter describes exchange processes and determination of ligand conformation and protein-ligand contacts. Nuclear magnetic resonance (NMR) spectroscopy can provide information on many different aspects of protein-ligand interactions, ranging from the determination of the complete structure of a protein-ligand complex to ...
Lian, LY   +4 more
openaire   +6 more sources

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