Results 381 to 390 of about 2,296,826 (424)
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Cannabinergic ligands

Chemistry and Physics of Lipids, 2002
The understanding of the pharmacology surrounding the cannabinergic system has seen many advances since the discovery of the CB1 receptor in the mammalian brain and the CB2 receptor in the periphery. Among these advances is the discovery of the endogenous ligands arachidonoylethanolamide (anandamide) and 2-arachidonoylglycerol amide (2-AG), which are ...
Sonya L, Palmer   +2 more
openaire   +2 more sources

Origin of the Substitution Mechanism for the Binding of Organic Ligands on the Surface of CsPbBr3 Perovskite Nanocubes.

Journal of Physical Chemistry Letters, 2017
Optoelectronic properties of CsPbBr3 perovskite nanocubes (NCs) depend strongly on the interaction of the organic passivating molecules with the inorganic crystal.
V. K. Ravi   +7 more
semanticscholar   +1 more source

Integrins and Their Ligands

1993
Integrins are expressed on almost every cell type and are responsible for the linkage of the extracellular matrix with the cytoskeleton. In this review I have focused on the intra- and extracellular proteins that bind to integrins. Although many integrins bind to the same extracellular ligand, they mostly recognize different sites on these ligands ...
openaire   +3 more sources

A Ligand, Not a Carrier [PDF]

open access: possibleScience, 2008
Volatile odorants are generally thought to bind to G protein-coupled receptors and thereby activate a downstream signaling pathway, a paradigm challenged by data from Laughlin et al . In Drosophila , various odorant-binding proteins are secreted into the lymph around subsets of olfactory ...
openaire   +2 more sources

Nuclear-Receptor Ligands and Ligand-Binding Domains

Annual Review of Biochemistry, 1999
▪ Abstract  The determination of several structures of nuclear receptor ligand binding domains (LBD) has led to new insights into the mechanism of action of this very important class of receptors. This review describes and compares the different LBD structures and their relationship to the function of the nuclear receptors.
R V, Weatherman   +2 more
openaire   +2 more sources

ProPose: Steered Virtual Screening by Simultaneous Protein—Ligand Docking and Ligand—Ligand Alignment. [PDF]

open access: possibleChemInform, 2005
The 'model-free' screening engine ProPose implements a general method for performing simultaneous protein-ligand docking, ligand-ligand alignment, pharmacophore queries-and combinations thereof-in order to incorporate a priori information into screening protocols.
openaire   +3 more sources

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes.

Journal of the American Chemical Society, 2016
The vastly increasing application of chiral Cp ligands in asymmetric catalysis results in growing demand for novel chiral Cp ligands. Herein, we report a new class of chiral Cp ligands based on 1,1'-spirobiindane, a privileged scaffold for chiral ligands
Jun-Cheng Zheng   +3 more
semanticscholar   +1 more source

[23] Protein-ligand interactions: Exchange processes and determination of ligand conformation and protein-ligand contacts

1994
Publisher Summary This chapter describes exchange processes and determination of ligand conformation and protein-ligand contacts. Nuclear magnetic resonance (NMR) spectroscopy can provide information on many different aspects of protein-ligand interactions, ranging from the determination of the complete structure of a protein-ligand complex to ...
Lian, LY   +4 more
openaire   +6 more sources

Nitrogen ligands

Dalton Transactions, 2019
This special web collection of Dalton Transactions focuses on nitrogen ligands, as a tribute to the 150th anniversary of the development of the periodic table.
openaire   +2 more sources

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