Results 41 to 50 of about 860,212 (198)

Functionalization of PET and WPET Nanofibres Grafted with oPrPy for the Recovery of Cu²⁺ Ions from Aqueous Solution

Proceedings, 2020
The plastic and metal pollution accumulating in the marine environment has given many researchers motivation to investigate and provide solutions to this problem. [...]
Thandiwe Crystal Totito, Katri Laatikainen, Robert Luckay, Omoniyi Pereao, Chris Bode-Aluko, Leslie Petrik   +5 more
doaj   +1 more source

Ligand-based CAR-T cell: Different strategies to drive T cells in future new treatments

Frontiers in Immunology, 2022
Chimeric antigen receptor (CAR)-based therapies are presented as innovative treatments for multiple malignancies. Despite their clinical success, there is scientific evidence of the limitations of these therapies mainly due to immunogenicity issues ...
Alejandro Ramírez-Chacón, Alejandro Ramírez-Chacón, Sergi Betriu-Méndez, Sergi Betriu-Méndez, Ariadna Bartoló-Ibars, Ariadna Bartoló-Ibars, Azucena González, Azucena González, Azucena González, Mercè Martí, Mercè Martí, Manel Juan, Manel Juan, Manel Juan   +13 more
doaj   +1 more source

Nuclear Hormone Receptors and Their Ligands: Metabolites in Control of Transcription

Cells, 2020
Nuclear hormone receptors are a family of transcription factors regulated by small molecules derived from the endogenous metabolism or diet. There are forty-eight nuclear hormone receptors in the human genome, twenty of which are still orphans.
Lian Jing Tao, Dong Eun Seo, Benjamin Jackson, Natalia B. Ivanova, Fabio Rinaldo Santori   +4 more
doaj   +1 more source

Comparison Studies on Several Ligands Used in Determination of Cd(II) in Rice by Flame Atomic Absorption Spectrometry after Ultrasound-Assisted Dispersive Liquid–Liquid Microextraction

Molecules, 2022
Ligands plays an important role in the extraction procedures for the determination of cadmium in rice samples by using flame atomic absorption spectrometry (FAAS).
Qian Sun, Xinyu Cui, Yanfeng Wang, Pingping Zhang, Wenjuan Lu   +4 more
doaj   +1 more source

Predicting the biological activity of selected phytochemicals in Alsophila spinulosa leaves against 4-aminobutyrate-aminotransferase: A potential antiepilepsy agents

Eclética Química
The use of medicinal plants as an alternative mean of treating various diseases has drawn the attention of several researchers. The desire to find lasting solutions to epilepsy among humans increases every day.
Oyebamiji Abel Kolawole, Olujinmi Faith Eniola, Akintelu Sunday Adewale, Adetuyi Babatunde, Ogunlana Olubanke, Semire Banjo, Akintayo Emmanuel Temitope, Akintayo Cecilia Olufunke, Babalola Jonathan Oyebamiji, Olawoye Bolanle Mary, Aworinde Juliana Oluwasayo   +10 more
doaj   +1 more source

Ligand‐dependent ribozymes [PDF]

WIREs RNA, 2016
The discovery of catalytic RNA (ribozymes) more than 30 years ago significantly widened the horizon of RNA‐based functions in natural systems. Similarly to the activity of protein enzymes that are often modulated by the presence of an interaction partner, some examples of naturally occurring ribozymes are influenced by ligands that can either act as ...
Felletti, Michele, Hartig, Jörg S.
openaire   +3 more sources

Selectin ligands. [PDF]

Proceedings of the National Academy of Sciences, 1994
The selectins initiate many critical interactions among blood cells. The volume of information and diversity of opinions on the nature of the biologically relevant ligands for selectins is remarkable. This review analyzes the matter and suggests the hypothesis that at least some of the specificity may involve recognition of "clustered saccharide ...
openaire   +3 more sources

Accurate Prediction of Drug Activity by Computational Methods: Importance of Thermal Capacity

Molecules
Heat capacity is one of the most important thermodynamic quantities in protein biochemistry. Upon the binding of small molecules, a change in the heat capacity of proteins is generally observed, and this is often used in drug discovery.
Luigi Leonardo Palese
doaj   +1 more source

Ligand-receptor interactions [PDF]

Reports on Progress in Physics, 1999
The formation and dissociation of specific noncovalent interactions between a variety of macromolecules play a crucial role in the function of biological systems. During the last few years, three main lines of research led to a dramatic improvement of our understanding of these important phenomena.
openaire   +4 more sources

Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) in Keratinocytes by Endogenous Fatty Acids

Biomolecules
Nuclear hormone receptors exist in dynamic equilibrium between transcriptionally active and inactive complexes dependent on interactions with ligands, proteins, and chromatin.
Bokai Zhu, Xiaoyang Zhu, Michael G. Borland, Douglas H. Ralph, Christopher R. Chiaro, Kristopher W. Krausz, James M. Ntambi, Adam B. Glick, Andrew D. Patterson, Gary H. Perdew, Frank J. Gonzalez, Jeffrey M. Peters   +11 more
doaj   +1 more source