Results 31 to 40 of about 2,177,035 (249)

Impact of pericardial fluid glucose level and computed tomography attenuation values on diagnosis of malignancy-related pericardial effusion

BMC Cardiovascular Disorders, 2021
Background We evaluated malignancy according to the characteristics of pericardial fluid in symptomatic Japanese patients undergoing pericardiocentesis and computed tomography (CT).
Takashi Nakamura, Mana Okune, Masakazu Yasuda, Heitaro Watanabe, Masafumi Ueno, Kenji Yamaji, Kazuki Mizutani, Takashi Kurita, Gaku Nakazawa   +8 more
doaj   +1 more source

Correspondence: Association of Light’s Criteria with Pleural Fluid Procalcitonin Levels and Ultrasound Thorax with its Impact on the Management of Pleural Effusion: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Dear Editor, The study titled “Association of Light’s Criteria with Pleural Fluid Procalcitonin Levels and Ultrasound (USG) Thorax with Its Impact on the Management of Pleural Effusion: A Cross-sectional Study”was read with great interest [1].
Kundan Mehta, Somireddy Navothna
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Pleural Fluid Cholesterol and Lactate Dehydrogenase to Differentiate Exudates and Transudate and Comparing it with Light’s Criteria [PDF]

, 2016
BACKGROUND: Light’s criteria is the routinely used criteria to differentiate exudative and transudative pleural effusion. It requires four biochemical parameters for estimation which may not be feasible in developing countries like India, due to ...
Manian, R B S
core  

Criteria preprocessing in multi‐actor multi‐criteria analysis

, 2023
Multi-actor multi-criteria analysis is a group decision-making framework that allows multiple stakeholder groups to be involved in the decision-making process, facilitating the understanding of the points of consensus and conflict among the stakeholder ...
Nicolas Brusselaers, Huang, He,, Canoy, Rocsildes,, Brusselaers, Nicolas,, Rocsildes Canoy, He Huang, Geert te Boveldt, Te Boveldt, Geert,   +7 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Revisiting Light's criteria: a validated blood-free triple combination matches diagnostic accuracy in over 7000 patients

ERJ Open Research
Background Light's criteria remain the standard for distinguishing exudative from transudative pleural effusions, but require serum sampling and lack specificity.
José M. Porcel, Laura Porcel, Rosa Palma, Silvia Bielsa   +3 more
doaj   +1 more source