Results 51 to 60 of about 5,336,418 (265)
Exploiting multimode waveguides for pure fibre-based imaging [PDF]
, 2012 We acknowledge support from the UK Engineering and Physical Science Research CouncilThere has been an immense drive in modern microscopy towards miniaturisation and fibre based technology.
Tomáš Čižmár +3 more
core +1 more source
Temporal resolution doubling in fluorescence light-sheet microscopy via a hue-encoded shutter and regularization [PDF]
, 2020 Studying dynamic biological processes, such as heart development and function in zebrafish embryos, often relies on multi-channel fluorescence labeling to distinguish multiple anatomical features, yet also demands high frame rates to capture rapid cell ...
Mercader, Nadia +3 more
core +2 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Photonics, 2021 Stimuli to excitable cells and various cellular processes can cause cell surface deformations; for example, when excitable cell membrane potentials are altered during action potentials.
Mariana Potcoava +3 more
doaj +1 more source
Attenuation artifacts in light sheet fluorescence microscopy corrected by OPTiSPIM [PDF]
Light: Science & Applications, 2018 AbstractLight sheet fluorescence microscopy (LSFM) is rapidly becoming an essential technology for mesoscopic imaging of samples such as embryos and adult mouse organs. However, LSFM can suffer from optical artifacts for which there is no intrinsic solution.
Mayer, Jürgen, 1977- +3 more
openaire +3 more sources
Light sheet fluorescence microscopy for in situ cell interaction analysis in mouse lymph nodes. [PDF]
, 2016 Reactive lymph nodes (LNs) are sites where pMHC-loaded dendritic cells (DCs) interact with rare cognate T cells, leading to their clonal expansion. While DC interactions with T cell subsets critically shape the ensuing immune response, surprisingly ...
Stein, Jens V. +7 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Cells, 2021 Cortical dysplasias are alterations in the organization of the layers of the brain cortex due to problems in neuronal migration during development. The neuronal component has been widely studied in experimental models of cortical dysplasias. In contrast,
Cynthia Alejandra Rodríguez-Arzate +5 more
doaj +1 more source
Light-Sheet Fluorescence Microscopy with Scanning Non-diffracting Beams [PDF]
Scientific Reports, 2019 Abstract Light-sheet fluorescence microscopy (LSFM) has now become a unique tool in different fields ranging from three-dimensional (3D) tissue imaging to real-time functional imaging of neuronal activities. Nevertheless, obtaining high-quality artifact-free images from large, dense and inhomogeneous samples is the main challenge of ...
Kafian, Hosein +4 more
openaire +2 more sources