Results 61 to 70 of about 8,570,567 (357)

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Tumor-dependent myeloid and lymphoid cell recruitment in genO-BRGSF-HIS mice: a novel tool for evaluating immunotherapies

Frontiers in Immunology
ObjectivesPreclinical models that accurately recapitulate the human immune response, particularly within the tumor microenvironment (TME), are needed for the translational and predictive testing of new therapies.
Gaëlle H. Martin, Siham Hedir, Florent Creusat, Alexis Gonon, Amélie Marguier, Perrine Martin-Jeantet, Lise Nouveau, Laura Cons, Florence Renart-Depontieu, Valery Moine, Marc Derive, Yacine Cherifi, Margarida T. Grilo Ruivo, Fabiane Sônego, Kader Thiam   +14 more
doaj   +1 more source

Light Chain (AL) Amyloidosis Masquerading as Scleroderma: A Diagnostic Challenge. [PDF]

J Hematol
Dhamija K, Jiwani RA, Lakshaman A, Sadashiv S, Mewawalla P.   +4 more
europepmc   +3 more sources

Light Chain Amyloidosis

Mediterranean Journal of Hematology and Infectious Diseases, 2018
Light chain (AL) amyloidosis is caused by a usually small plasma-cell clone that is able to produce the amyloidogenic light chains. They are able to misfold and aggregate, deposit in tissues in the form of amyloid fibrils and lead to irreversible organ ...
P. Milani, G. Merlini, G. Palladini
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Immunoglobulin Light Chain Gene Rearrangements, Receptor Editing and the Development of a Self-Tolerant Antibody Repertoire

Frontiers in Immunology, 2018
Discussion of the antibody repertoire usually emphasizes diversity, but a conspicuous feature of the light chain repertoire is its lack of diversity. The diversity of reported allelic variants of germline light chain genes is also limited, even in well ...
A. Collins, C. Watson
semanticscholar   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Strong electron-photon coupling in one-dimensional quantum dot chain: Rabi waves and Rabi wavepackets [PDF]

, 2009
We predict and theoretically investigate the new coherent effect of nonlinear quantum optics -- spatial propagation of Rabi oscillations (Rabi waves) in one-dimensional quantum dot (QD) chain.
A. Hoffmann, A. Kavokin, C. Cohen-Tannoudji, E. M. Lifshitz, F. G. Bass, G. Ya. Slepyan, L. Allen, L. Novotny, M. O. Scully, Ph. A. Martin, R. Loudon, S. M. Dutra, Y. D. Yerchak, Y. R. Shen   +13 more
core   +1 more source

Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia

Neurology, 2016
Objective: To investigate serum neurofilament light chain (NfL) concentrations in frontotemporal dementia (FTD) and to see whether they are associated with the severity of disease.
J. Rohrer, I. Woollacott, K. Dick, E. Brotherhood, E. Gordon, Alexander Fellows, J. Toombs, R. Druyeh, M. Jorge Cardoso, S. Ourselin, Jennifer M. Nicholas, N. Norgren, S. Mead, U. Andreasson, K. Blennow, J. Schott, Nick C Fox, J. Warren, H. Zetterberg   +18 more
semanticscholar   +1 more source