Results 81 to 90 of about 2,711,435 (306)

Analysis of the conditional mutual information in ballistic and diffusive non-equilibrium steady-states [PDF]

, 2019
The conditional mutual information (CMI) $\mathcal{I}(A\! : \! C|B)$ quantifies the amount of correlations shared between $A$ and $C$ \emph{given} $B$.
Adesso, Gerardo, Goold, John, Landi, Gabriel T., Malouf, William T. B.   +3 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Tuning oxidative stability and digestibility of frozen myofibrillar protein: A combined magnetic field and pH-shifting approach

Food Chemistry: X
This study investigated the synergistic effects of magnetic field (MF) and pH-shifting (pH 9–11) on the oxidative stability and in vitro digestibility of frozen denatured myofibrillar protein (MP).
Bo Chen, Shanshan Huangfu, Jiayi Cai, Wen Nie, Ke Li, Yu Wang, Yanhong Bai   +6 more
doaj   +1 more source

Optical Properties of Collective Excitations for Finite Chains of Trapped Atoms

, 2011
Resonant dipole-dipole interaction modifies the energy and decay rate of electronic excitations for finite one dimensional chains of ultracold atoms in an optical lattice.
A. Goban, C. Weitenberg, D. Jaksch, E. Vetsch, G. Sague, H. Ritsch, H. Zoubi, H. Zoubi, H. Zoubi, H. Zoubi, H. Zoubi, H. Zoubi, H. Zoubi, H. Zoubi, H. Zoubi, I. Bloch, I.B. Spielman, J.F. Sherson, K.P. Nayak, M. Greiner, M. Lewenstein, W.S. Bakr   +21 more
core   +1 more source

A role for Tctex-1 (DYNLT1) in controlling primary cilium length [PDF]

, 2011
The microtubule motor complex cytoplasmic dynein is known to be involved in multiple processes including endomembrane organization and trafficking, mitosis, and microtubule organization.
MacCarthy-Morrogh, LJ, Miss Nicola, Smyllie, Palmer, KJ, Stephens, DJ   +3 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The role of notch signaling pathway in cancer: mechanistic insights, therapeutic potential, and clinical progress

Frontiers in Immunology
This article presents a comprehensive literature review on the role of the Notch signaling pathway in cancer and its molecular mechanisms. The Notch signaling pathway plays an important role in various types of cancer by regulating key biological ...
Haokun Zhang, Haokun Zhang, Haokun Zhang, Wang Hang, Wang Hang, Wang Hang, ZhaoHui Jing, ZhaoHui Jing, ZhaoHui Jing, Bingyan Liu, Bingyan Liu, Bingyan Liu, Xiaoxiao Wang, Xiaoxiao Wang, Xiaoxiao Wang, Yilin Li, Yilin Li, Yilin Li, Huomin Luo, Huomin Luo, Huomin Luo, Huilin Lv, Huilin Lv, Huilin Lv, Xingyue Tao, Xingyue Tao, Xingyue Tao, Peter Timashev, Yuzhen Li, Peifeng Li, Peifeng Li, Peifeng Li   +31 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Research on the Influence of Moisture State, Microscopic Morphology and Physical Properties of the Resting Dough

Shipin gongye ke-ji
To study the effect of resting on the quality of frozen dough, the changes in the moisture state of the dough during the resting process (0, 30, 60, 90, 120 min), the moisture distribution of dough and their effects on ice crystal distribution ...
Yanyan ZHANG, Jie ZHANG, Jing ZHANG, Pu ZHANG, Xingli LIU, Hua ZHANG   +5 more
doaj   +1 more source