Results 121 to 130 of about 1,812,631 (345)

Understanding Gamma-ray Burst Jet Structures from Afterglow Light Curves [PDF]

, 2021
Celia R. Tandon, Nicole Lloyd-Ronning
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Predicted Light Curves for a Model of Solar Eruptions [PDF]

, 2005
Katharine K. Reeves, T. G. Forbes
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Spectra and Light Curves of GRB Afterglows

, 2004
We performed accurate numerical calculations of angle-, time-, and frequency-dependent radiative transfer for the relativistic motion of matter in gamma-ray burst (GRB) models. Our technique for solving the transfer equation, which is based on the method
A. G. Tolstov, B. L. Jensen, D. Mihalas, E. Waxman, G. B. Rybicki, H. Spruit, J. Granot, J. Granot, K. A. Postnov, K. Z. Stanek, M. J. Rees, M. J. Rees, P. Mészáros, R. A. M. J. Wijers, R. Blandford, R. D. Blandford, R. Sari, S. I. Blinnikov, S. I. Blinnikov, S. I. Blinnikov, T. P. Downes, T. Piran, V. V. Usov   +22 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

X-Ray Light Curves of Gamma-ray Bursts Detected with the All-Sky Monitor on RXTE

, 2002
We present X-ray light curves (1.5-12 keV) for fifteen gamma-ray bursts (GRBs) detected by the All-Sky Monitor on the Rossi X-ray Timing Explorer. We compare these soft X-ray light curves with count rate histories obtained by the high-energy (>12 keV ...
A. Levine, Aptekar R., Cavallo G., D. A. Smith, G. Pendleton, H. Bradt, Hurley K., K. Hurley, M. Feroci, Murakami T., Nicastro L., P. Butterworth, Piro L., Piro L., Rees M., S. Golenetskii, S. Phengchamnan, Seward F.   +17 more
core   +1 more source

Wavelet-based filter methods to detect small transiting planets in stellar light curves [PDF]

, 2016
S. Grziwa, M. Pätzold
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A FURTHER INVESTIGATION OF APPARENT PERIODICITIES AND THE ROTATIONAL STATE OF COMET 103P/HARTLEY 2 FROM COMBINED COMA MORPHOLOGY AND LIGHT CURVE DATA SETS [PDF]

, 2015
Matthew M. Knight, B. E. A. Mueller, Nalin H. Samarasinha, D. G. Schleicher   +3 more
openalex   +1 more source