Results 191 to 200 of about 38,595 (230)

Water‐Mediated Phosphoryl Wires Stabilize Pathological Tau Fibrils

Angewandte Chemie, EarlyView.
Extended 1D phosphoryl “wires” stabilize in‐register amyloid tau fibrils, as demonstrated by multiple‐quantum spin‐counting NMR, TEM, and MD simulations, using fibrils of tau peptide jR2R3‐P301L (tau295–313) with phosphorylation at S305 or Y310. ABSTRACT Hyperphosphorylation of tau is a hallmark of tauopathies, with specific phosphorylation sites ...
Lokeswara Rao Potnuru, Austin DuBose, Fiona Mon, Mesopotamia S. Nowotarski, Michael Vigers, Boqin Zhang, Chung‐Ta Han, John E. Straub, Songi Han   +8 more
wiley   +2 more sources

Multi‐Responsive Bowl‐Shaped Janus Nanomotors Based on Polyitaconic acid/Polypyrrole on the Surface of Iron Oxide Nanoparticles with Chemical, Electrical, and Magnetic Field Actuation for Targeted Drug Delivery Applications

Advanced NanoBiomed Research, EarlyView.
Bowl‐shaped Janus nanomotors with platinum, iron oxide, and polypyrrole integrate catalytic, magnetic, and electric propulsion for targeted drug delivery. They demonstrate controlled, directional motion under varying pH and hydrogen peroxide conditions, with optimal performance in neutral media.
Kimia Tavakoli Dehaghi, Sepideh Khoee, Shima Tavakoli, Oommen P. Varghese   +3 more
wiley   +1 more source

Intrinsically Ultrahigh‐Rate Charging Capability of Conversion Reaction Cathodes and Its Origin: A Mechanism Study on FeS2

Carbon Energy, EarlyView.
Origin of the ultrahigh‐rate charge capability of FeS2: FeS2 demonstrates exceptional high‐rate charging capability, delivering 92% capacity retention at 10 C and maintaining as much as 60% capacity retention even at 30 C. This originates from an ultrahigh apparent diffusion coefficient involving both Li+ and Fe2+.
Zhen Yu, Junxiong Chen, Zongwang Tian, Ji Li, Yicheng Wang, Lifu Shen, Jianwei Meng, Kaiyu Zhang, Jingyi Xie, Nian Zhang, Xuefei Feng, Tsu‐Chien Weng, Xiaosong Liu, Pengfei Yu   +13 more
wiley   +1 more source

Carbon Quantum Dots Meet Perovskite Solar Cells: A Review of Multifunctional Synergies

Carbon Energy, EarlyView.
This review highlights the multifunctional role of carbon dots in perovskite solar cells. Their applications as additives and interfacial modifiers are discussed in terms of crystallization control, defect passivation, energy‐level alignment, and environmental stability.
Yagmur Su Sayin, Matteo Bonomo, Nilgun Karatepe, Marta Feroci   +3 more
wiley   +1 more source

Engineered Carbon Dots as Multifunctional Nanoplatforms for Next‐Generation High‐Performance Advanced Batteries

Carbon Energy, EarlyView.
Herein, we mainly summarize the characteristics of the main types of carbon dots (CDs), analyze the strategies for improving advanced batteries' performance via incorporating CDs, comprehensively summarize recent applications of CDs in the main components (electrode, electrolyte, and separator) of advanced batteries, and propose the technical ...
Chuang Jiang, Jinlong Feng, Zhenjie Liu, Ming Jia, Qingxi Hou, Wei Liu   +5 more
wiley   +1 more source

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Light sheet fluorescence microscopy

Nature Reviews Methods Primers, 2021
Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical sectioning capability and, hence, provide axial resolution, restrict photobleaching and phototoxicity to a fraction of the sample and use cameras to record tens to thousands of ...
Ernst H K Stelzer, Frédéric Strobl, Bo-Jui Chang   +2 more
exaly   +4 more sources

Light Sheet Fluorescence Microscopy [PDF]

Journal of Histochemistry and Cytochemistry, 2011
Light sheet fluorescence microscopy (LSFM) functions as a non-destructive microtome and microscope that uses a plane of light to optically section and view tissues with subcellular resolution. This method is well suited for imaging deep within transparent tissues or within whole organisms, and because tissues are exposed to only a thin plane of light ...
exaly   +3 more sources

Nonlinear light-sheet fluorescence microscopy by photobleaching imprinting [PDF]

Journal of the Royal Society Interface, 2014
Abstract We present a nonlinear light-sheet fluorescence microscopy (LSFM) scheme based on photobleaching imprinting. By measuring photobleaching-induced fluorescence decay, our method simultaneously achieves a large imaging field of view and a thin optical section.
Liren Zhu, Chiye Li, Lihong V Wang
exaly   +4 more sources

A guide to light-sheet fluorescence microscopy for multiscale imaging

Nature Methods, 2017
The impact of light-sheet fluorescence microscopy (LSFM) is visible in fields as diverse as developmental and cell biology, anatomical science, biophysics and neuroscience. Although adoption among biologists has been steady, LSFM has not displaced more traditional imaging methods despite its often-superior performance.
Rory M Power, Jan Huisken, Huisken Jan
exaly   +5 more sources

Light-sheet fluorescence microscopy for quantitative biology

Nature Methods, 2014
In light sheet–based fluorescence microscopy (LSFM), optical sectioning in the excitation process minimizes fluorophore bleaching and phototoxic effects. Because biological specimens survive long-term three-dimensional imaging at high spatiotemporal resolution, LSFM has become the tool of choice in developmental biology.
Ernst H K Stelzer, Stelzer Ernst H K
exaly   +3 more sources