Results 191 to 200 of about 136,404 (276)

Illuminating Satellite Cells: Light Sheet Fluorescence Microscopy for 3D Imaging of Murine Skeletal Muscles Damaged by Ex Vivo Forced Eccentric Contraction. [PDF]

Microsc Res Tech
Garella R, Imbimbo E, Palmieri F, Tani A, Parigi M, Chellini F, La Contana A, Belmonte MM, Longhin A, Silvestri L, Sassoli C, Squecco R.   +11 more
europepmc   +1 more source

Erratum: Deep learning-based autofocus method enhances image quality in light-sheet fluorescence microscopy: publisher's note. [PDF]

Biomed Opt Express, 2022
Li C, Moatti A, Zhang X, Ghashghaei HT, Greenbaum A.   +4 more
europepmc   +1 more source

CD28‐Targeted Enzyme‐Responsive Conformation‐Switching Peptide Self‐Assembly for Selective T‐Cell Acute Lymphoblastic Leukemia (T‐ALL) Therapy

Advanced Science, EarlyView.
We developed the enzyme‐responsive peptide SAp‐CD28 to selectively target CD28‐overexpressing T‐ALL cells. Following phosphatase‐mediated activation, SAp‐CD28 undergoes conformational switching and nanooligomerization, resulting in the disruption of CD28 downstream signaling.
Jun Li, Ziyu Jia, Dekun Li, Zhi‐Wen Hu, Yinghao Ding, Shengyi Zhang, Shengkun Tuo, Zhimou Yang, Huisheng Fu, Ling Wang, Man‐Di Wang   +10 more
wiley   +1 more source

First application of three-dimensional light sheet fluorescence microscopy to human testicular tumors: New perspectives in histopathology. [PDF]

Andrology
Pinkert-Leetsch D, Kareem A, Merz SF, Teckentrup M, Fichtner A, Bremmer F, Missbach-Guentner J.   +6 more
europepmc   +1 more source

Two-photon scanned light sheet fluorescence microscopy with axicon imaging for fast volumetric imaging. [PDF]

J Biomed Opt, 2021
Lin PY, Hwang SL, Lee CH, Chen BC.
europepmc   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Three-Dimensional β-Amyloid Burden Correlation Between the Eye and Brain in Alzheimer's Disease Mice Using Light-Sheet Fluorescence Microscopy. [PDF]

Invest Ophthalmol Vis Sci
Son HJ, Kim S, Kim SY, Jung JH, Lee SH, Kim SJ, Kim C, Hahn A.   +7 more
europepmc   +1 more source

Multimodal high-resolution embryonic imaging with light sheet fluorescence microscopy and optical coherence tomography. [PDF]

Opt Lett, 2021
Khajavi B, Sun R, Chawla HS, Le HH, Singh M, Schill AW, Dickinson ME, Mayerich D, Larin KV.   +8 more
europepmc   +1 more source