Results 21 to 30 of about 4,952,727 (242)
A Versatile Tiling Light Sheet Microscope for Imaging of Cleared Tissues
Summary: We present a tiling light sheet microscope compatible with all tissue clearing methods for rapid multicolor 3D imaging of cleared tissues with micron-scale (4 × 4 × 10 μm3) to submicron-scale (0.3 × 0.3 × 1 μm3) spatial resolution. The resolving
Yanlu Chen +17 more
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Light-sheets and smart microscopy, an exciting future is dawning
Light-sheet fluorescence microscopy has transformed our ability to visualize and quantitatively measure biological processes rapidly and over long time periods.
Stephan Daetwyler, Reto Paul Fiolka
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Whole-central nervous system functional imaging in larval Drosophila [PDF]
This work was supported by the Howard Hughes Medical Institute.Understanding how the brain works in tight concert with the rest of the central nervous system (CNS) hinges upon knowledge of coordinated activity patterns across the whole CNS.
Pulver, Stefan +6 more
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Applications of Light-Sheet Microscopy in Microdevices
Light-sheet fluorescence microscopy (LSFM) has been present in cell biology laboratories for quite some time, mainly as custom-made systems, with imaging applications ranging from single cells (in the micrometer scale) to small organisms (in the ...
Ignacio Albert-Smet +11 more
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Three dimensional fluorescence imaging using multiple light-sheet microscopy. [PDF]
We developed a multiple light-sheet microscopy (MLSM) system capable of 3D fluorescence imaging. Employing spatial filter in the excitation arm of a SPIM system, we successfully generated multiple light-sheets. This improves upon the existing SPIM system
Kavya Mohan +2 more
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Biobeam-Multiplexed wave-optical simulations of light-sheet microscopy. [PDF]
Sample-induced image-degradation remains an intricate wave-optical problem in light-sheet microscopy. Here we present biobeam, an open-source software package that enables simulation of operational light-sheet microscopes by combining data from 105-106 ...
Martin Weigert +4 more
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Bessel Light Sheet Structured Illumination Microscopy
Biomedical study researchers using animals to model disease and treatment need fast, deep, noninvasive, and inexpensive multi-channel imaging methods. Traditional fluorescence microscopy meets those criteria to an extent.
Noshirvani Allahabadi, Golchehr
core +5 more sources
ADVANCED OPTICAL TECHNIQUES TO EXPLORE BRAIN STRUCTURE AND FUNCTION [PDF]
Understanding brain structure and function, and the complex relationships between them, is one of the grand challenges of contemporary sciences. Thanks to their flexibility, optical techniques could be the key to explore this complex network.
L. SILVESTRI +4 more
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Deep tissue light-sheet microscopy [PDF]
Light-sheet fluorescence microscopy, also recognised as selective plane illumination microscopy, or SPIM, has paved a new road towards imaging of entire specimens for long periods of time, in vivo.
Quintas Glasner de Medeiros, Gustavo
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Light Sheet Reflectance Microscopy
Many human diseases are diagnosed by the histopathological analysis of suspicious lesions where cellular morphological changes are examined at microscopic resolution.
Nguyen, Christopher David
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