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AP2/ERF Transcription Factor, Ii049, Positively Regulates Lignan Biosynthesis in Isatis indigotica through Activating Salicylic Acid Signaling and Lignan/Lignin Pathway Genes

open access: yesFrontiers in Plant Science, 2017
Lignans, such as lariciresinol and its derivatives, have been identified as effective antiviral ingredients in Isatis indigotica. Evidence suggests that the APETALA2/ethylene response factor (AP2/ERF) family might be related to the biosynthesis of ...
Hexin Tan, Ruibing Chen, Wansheng Chen
exaly   +4 more sources

Essences in Metabolic Engineering of Lignan Biosynthesis

open access: yesMetabolites, 2015
Lignans are structurally and functionally diverse phytochemicals biosynthesized in diverse plant species and have received wide attentions as leading compounds of novel drugs for tumor treatment and healthy diets to reduce of the risks of lifestyle ...
Honoo Satake   +2 more
exaly   +4 more sources

Naturally Lignan-Rich Foods: A Dietary Tool for Health Promotion?

open access: yesMolecules, 2019
Dietary guidelines universally advise adherence to plant-based diets. Plant-based foods confer considerable health benefits, partly attributable to their abundant micronutrient (e.g., polyphenol) content. Interest in polyphenols is largely focused on the
Carmen Rodríguez-garcía   +2 more
exaly   +2 more sources

A Novel Soybean Dirigent Gene GmDIR22 Contributes to Promotion of Lignan Biosynthesis and Enhances Resistance to Phytophthora sojae

open access: yesFrontiers in Plant Science, 2017
Phytophthora root and stem rot caused by the oomycete pathogen Phytophthora sojae is a destructive disease of soybean worldwide. Plant dirigent proteins (DIR) are proposed to have roles in biosynthesis of either lignan or lignin-like molecules, and are ...
Shuzhen Zhang
exaly   +2 more sources

Effects of a Flaxseed-Derived Lignan Supplement in Type 2 Diabetic Patients: A Randomized, Double-Blind, Cross-Over Trial [PDF]

open access: yesPLoS ONE, 2007
Flaxseed consumption has been shown to improve blood lipids in humans and flaxseed-derived lignan has been shown to enhance glycemic control in animals. The study aimed to investigate the effect of a flaxseed-derived lignan supplement on glycemic control,
An Pan
exaly   +2 more sources

Flavonoid and lignan intake in relation to bladder cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study [PDF]

open access: yesBritish Journal of Cancer, 2014
Item does not contain fulltextBACKGROUND: There is growing evidence of the protective role of dietary intake of flavonoids and lignans on cancer, but the association with bladder cancer has not been thoroughly investigated in epidemiological studies.
A Crozier   +87 more
core   +6 more sources

Integrative analysis of the metabolome and transcriptome provides insights into the mechanisms of lignan biosynthesis in Herpetospermum pedunculosum (Cucurbitaceae) [PDF]

open access: yesBMC Genomics
Background Herpetospermum pedunculosum (Ser.) C. B. Clarke is a traditional Chinese herbal medicine that heavily relies on the lignans found in its dried ripe seeds (Herpetospermum caudigerum), which have antioxidant and hepatoprotective functions ...
Ziwei Zhu   +9 more
doaj   +2 more sources

Preparation of flaxseed for lignan determination by gas chromatography-mass spectrometry method

open access: yesCzech Journal of Food Sciences, 2012
Since 1980s, several methods for the determination of lignans in food samples have been developed depending on the types of lignans and foods analysed, but mostly on flaxseed as a reference food.
Hrvoje Sarajlija   +5 more
doaj   +2 more sources

A New Tetrahydrofuran Lignan Diglycoside from Viola tianshanica Maxim

open access: yesMolecules, 2013
A new lignan glycoside, tianshanoside A (1), together with a known phenylpropanoid glycoside, syringin (2) and two known lignan glycosides, picraquassioside C (3), and aketrilignoside B (4), were isolated from the whole plant of Viola tianshanica Maxim ...
Yan Qin, Chengle Yin, Zhihong Cheng
doaj   +2 more sources

Radiation mitigating properties of the lignan component in flaxseed [PDF]

open access: yesBMC Cancer, 2013
BACKGROUND: Wholegrain flaxseed (FS), and its lignan component (FLC) consisting mainly of secoisolariciresinol diglucoside (SDG), have potent lung radioprotective properties while not abrogating the efficacy of radiotherapy.
Charalambos C Solomides   +9 more
core   +2 more sources

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