Results 91 to 100 of about 26,355 (196)
Human‐umbilical‐cord‐mesenchymal‐stem‐cell‐derived exosomes amplify anti‐hepatocellular‐carcinoma effects of gallic acid from Compound Muji Granules. This work identifies absorbed herbal constituents and reveals modulation of IL‐17/MAPK/p53 signaling in HCC organoid models, offering mechanistic insights for exosome‐assisted traditional‐medicine ...
Qiang Zhang +12 more
wiley +1 more source
Modification of spruce lignans with Trametes hirsuta laccase
The effect of Trametes hirsuta laccase on isolated spruce wood lignans was evaluated. Lignans were isolated from the heartwood of spruce branches and treated with different laccase dosages and treatment times. The effect of the treatment was monitored by
Tamminen, Tarja +4 more
core +1 more source
The blood-brain barrier (BBB) permeability of twelve lignans and three phenolic malabaricones from the seeds of Myristica fragrans (nutmeg) were studied with the MDCK-pHaMDR cell monolayer model.
Ni Wu +5 more
doaj +1 more source
Polyphenol‐rich plant extracts provide natural immunomodulatory protection for oral health through complementary antioxidant, antibacterial, and anti‐inflammatory actions. Their potential to reduce harmful microbial activity and inflammation highlights the promise of dietary polyphenols as a natural strategy for maintaining oral health and preventing ...
Deepa Subramanian +3 more
wiley +1 more source
Valorization of Hot Trub: Extraction and Nanoparticle Encapsulation for Antitumor Applications
Hot trub, a brewing by‐product, is valorized through optimized extraction of phenolic compounds and encapsulation in zein nanoparticles. The polyphenol‐rich extract shows antioxidant and photoprotective activity (SPF 13.84), while zein‐based nanocarriers, particularly chitosan‐ and caseinate‐coated variants, extend its effect on MCF‐7 breast cancer ...
Lilian Tatiani Dusman Tonin +10 more
wiley +1 more source
Lignans, which are recognized as main constituents in Justicia procumbens, have attracted considerable attention due to their pharmacological activities, including antitumor, anti-hepatitic, cytotoxic, anti-microbial, and anti-virus properties ...
Peijuan Zhou +8 more
doaj +1 more source
Sesame Immunotherapy: A Systematic Review and Narrative Synthesis
ABSTRACT Sesame allergy is associated with severe allergic reactions, low rates of spontaneous resolution, and significant psychosocial burden. Current management relies on strict avoidance and emergency treatment. Allergen‐specific immunotherapy, particularly oral immunotherapy (OIT), has emerged as a potential disease‐modifying approach, but evidence
Joanna Zielińska +4 more
wiley +1 more source
Two new cyclobutane-type lignans, named moslolignans A and B, together with two known ones, andamanicin and magnosalin, were isolated from the whole plant of Mosla scabra.
Andrew Marston +9 more
core +1 more source
A New Triterpenoid from Teucrium viscidum
A new ursane-type triterpenoid, 3β-hydroxy-urs-30-p-Z-hydroxycinnamoyloxy-12-en-28-oic-acid (1), together with three known triterpenoids, 3β-hydroxy-urs-30-p-E-hydroxycinnamoyloxy-12-en-28-oic-acid (2), 2α,3β,19α-trihydroxy-urs-12-en-28-oic-acid (3), and
Yonghui Zhang +7 more
doaj +1 more source
Computational drug discovery integrates molecular docking, molecular dynamics simulations, and translational clinical targeting to identify next‐generation therapeutics that overcome endocrine resistance in ER‐positive breast cancer. Combined with multi‐omics, artificial intelligence, and biomarker‐guided precision oncology, these approaches accelerate
Emmanuel Ifeanyi Obeagu, Yaregal Asres
wiley +1 more source

