Results 101 to 110 of about 26,355 (196)
EBND alone upregulates neurofilament expression but does not induce neurite outgrowth in PC12 cells. With suboptimal NGF, EBND synergistically promotes neuronal differentiation via the TrkA‐ERK1/2‐CREB‐BDNF pathway. This effect is blocked by the TrkA inhibitor GW441756, confirming a TrkA‐dependent mechanism.
Wen Zhang +9 more
wiley +1 more source
Synthetic studies on optically active furofuran and diarylbutane lignans*
Lignans are a large class of naturally occurring secondary metabolites which are widely spread within the plant kingdom. Their diverse structures and variety of biological activities have fascinated organic chemists.
Naoki Mori
core +1 more source
Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass +2 more
wiley +1 more source
The hexane extract from the aerial parts of Aristolochia peltato-deltoidea Hoehne (Aristolochiaceae) afforded two new epimeric lignans of the type dibenzylbutyrolactol, rel-(8R, 8?S, 9S)-3,4-dimethoxy-3?,4?-methylenedioxy-9beta-ethoxy- and rel-(8R, 8?S ...
Silva Ana Paula Freitas da +3 more
doaj
The ethanolic leaf extract of Mouriri elliptica exhibited antibacterial and antibiofilm activities against multidrug‐resistant clinical isolates and enhanced the activity of ampicillin. Its diverse chemical profile and low acute toxicity support this Cerrado species as a promising source of natural antibacterial adjuvants. ABSTRACT Bacterial resistance
Talita Vilalva Freire +9 more
wiley +1 more source
The Isolation and oxidative coupling of lignans
Full text is available to authenticated members of The University of Auckland only.The first part of this work discusses the results of a re-examination of the lignan constituents contained in extracts of the wood of the New Zealand podocarp, Dacrydium ...
Craw, Peter Arne
core
Influenza A virus modulates host innate immune pathways, including TLR, RIG‐I, MAPK, and NF‐κB signaling, to support replication and drive inflammatory pathology. Plant‐derived phytocompounds target these interconnected pathways, offering a potential host‐directed immunomodulatory approach complementary to conventional antivirals.
Dibakar Chowdhury +3 more
wiley +1 more source
Serial‐passage testing in wound‐relevant bacteria showed that Norway spruce (Picea abies) resin did not produce confirmed resistance development under the conditions tested. These findings support spruce resin as a natural antimicrobial with low propensity to select resistance.
Kamilla Yamileva +3 more
wiley +1 more source
Introduction: Lignans, phenolic compounds that are present in a number of foodstuffs, possess some biological activities i.e., antioxidant and antiestrogenic [1,2].
Gianni Sagratini +5 more
core
Podophyllotoxin and Aryltetralin Lignans: Methods for the Synthesis of Rings A, B, C, D
Podophyllotoxin, its derivatives and structural analogues are an extensive group of aryl-tetralin-lignans of interest in pharmacology due to their promising anticancer and antitumor activity.
Francisco Flores-Hernández +4 more
doaj +1 more source

