Results 101 to 110 of about 26,355 (196)

Enzyme‐Digested Edible Bird's Nest Promotes NGF‐Induced Differentiation of PC12 Cells by Activating the TrkA‐ERK1/2‐CREB‐BDNF Signaling Pathway

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
EBND alone upregulates neurofilament expression but does not induce neurite outgrowth in PC12 cells. With suboptimal NGF, EBND synergistically promotes neuronal differentiation via the TrkA‐ERK1/2‐CREB‐BDNF pathway. This effect is blocked by the TrkA inhibitor GW441756, confirming a TrkA‐dependent mechanism.
Wen Zhang   +9 more
wiley   +1 more source

Synthetic studies on optically active furofuran and diarylbutane lignans*

open access: yes, 2018
Lignans are a large class of naturally occurring secondary metabolites which are widely spread within the plant kingdom. Their diverse structures and variety of biological activities have fascinated organic chemists.
Naoki Mori
core   +1 more source

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

open access: yesJournal of Chemical Technology &Biotechnology, Volume 101, Issue 10, Page 2072-2084, October 2026.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass   +2 more
wiley   +1 more source

Two Dibenzylbutyrolactol Derivatives and Other Chemical Constituents from Aristolochia peltato-deltoidea

open access: yesJournal of the Brazilian Chemical Society, 1999
The hexane extract from the aerial parts of Aristolochia peltato-deltoidea Hoehne (Aristolochiaceae) afforded two new epimeric lignans of the type dibenzylbutyrolactol, rel-(8R, 8?S, 9S)-3,4-dimethoxy-3?,4?-methylenedioxy-9beta-ethoxy- and rel-(8R, 8?S ...
Silva Ana Paula Freitas da   +3 more
doaj  

Adjuvant Antibacterial Effects of Mouriri Elliptica Against Clinical Multidrug Resistant Gram‐Negative Bacterial Strains

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
The ethanolic leaf extract of Mouriri elliptica exhibited antibacterial and antibiofilm activities against multidrug‐resistant clinical isolates and enhanced the activity of ampicillin. Its diverse chemical profile and low acute toxicity support this Cerrado species as a promising source of natural antibacterial adjuvants. ABSTRACT Bacterial resistance
Talita Vilalva Freire   +9 more
wiley   +1 more source

The Isolation and oxidative coupling of lignans

open access: yes, 1986
Full text is available to authenticated members of The University of Auckland only.The first part of this work discusses the results of a re-examination of the lignan constituents contained in extracts of the wood of the New Zealand podocarp, Dacrydium ...
Craw, Peter Arne
core  

Dual Antiviral and Immunomodulatory Effects of Phytochemicals in Influenza A Virus Infection: Targeting Key Host Signaling Pathways

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Influenza A virus modulates host innate immune pathways, including TLR, RIG‐I, MAPK, and NF‐κB signaling, to support replication and drive inflammatory pathology. Plant‐derived phytocompounds target these interconnected pathways, offering a potential host‐directed immunomodulatory approach complementary to conventional antivirals.
Dibakar Chowdhury   +3 more
wiley   +1 more source

Serial‐Passage Assessment Shows No Confirmed Resistance Development to Norway Spruce (Picea Abies) Resin in Bacterial Species Relevant to Wound Infection

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Serial‐passage testing in wound‐relevant bacteria showed that Norway spruce (Picea abies) resin did not produce confirmed resistance development under the conditions tested. These findings support spruce resin as a natural antimicrobial with low propensity to select resistance.
Kamilla Yamileva   +3 more
wiley   +1 more source

A NEW ANALYTICAL METHOD FOR THE QUANTIFICATION OF THREE LIGNANS IN ESPRESSO COFFEE BY USING HPLC-MS/MS TRIPLE QUADRUPOLE

open access: yes, 2018
Introduction: Lignans, phenolic compounds that are present in a number of foodstuffs, possess some biological activities i.e., antioxidant and antiestrogenic [1,2].
Gianni Sagratini   +5 more
core  

Podophyllotoxin and Aryltetralin Lignans: Methods for the Synthesis of Rings A, B, C, D

open access: yesЖурнал органічної та фармацевтичної хімії
Podophyllotoxin, its derivatives and structural analogues are an extensive group of aryl-tetralin-lignans of interest in pharmacology due to their promising anticancer and antitumor activity.
Francisco Flores-Hernández   +4 more
doaj   +1 more source

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