Results 121 to 130 of about 24,247 (252)
Podophyllotoxin and Aryltetralin Lignans: Methods for the Synthesis of Rings A, B, C, D
Podophyllotoxin, its derivatives and structural analogues are an extensive group of aryl-tetralin-lignans of interest in pharmacology due to their promising anticancer and antitumor activity.
Francisco Flores-Hernández +4 more
doaj +1 more source
New spirobenzofuranoid dibenzocyclooctadiene lignans from Kadsura oblongifolia
Two new spirobenzofuranoid dibenzocyclooctadiene lignans, kadsulignans O (1) and P (2) were isolated from the stems of Kadsura oblongifolia, together with five known same type lignans, kadsulignans C (3), E (4), F (5), G (6), and heteroclitin J (7 ...
Yaodong Qi +13 more
core +1 more source
Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley +1 more source
DHA and flaxseed oil reduce tumor sizes, superoxide dismutase activity, malondialdehyde level and increase white blood cells, platelets, serum protein level, glutathione peroxidase, nitric oxide, catalase activities in DMBA‐induced breast cancer in Wistar rats compared to the negative control.
Julia Ndifor Mebami +5 more
wiley +1 more source
Bajra‐based functional laddu—Standardization, nutritional profiling, molecular characterization
Abstract The bajra laddu experimental formulations consisted of composite flour containing varying proportions of bajra flour and gram flours viz, T0‐0:100, T1‐25:75, T2‐50:50, T3‐75:25, and T4‐100:0, respectively. The sensory acceptability of the standardized product was assessed by semitrained panelists using a nine‐point hedonic scale, which ...
Mridula Pandey +5 more
wiley +1 more source
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja +3 more
wiley +1 more source
Phyllanthus Lignans: A Review of Biological Activity and Elicitation
The Phyllanthus genus exhibits a broad distribution spanning across the majority of tropical and subtropical regions. Due to their ability to synthesize medicinal bioactive compounds such as lignans, they have been utilized historically in traditional ...
Winda Nawfetrias +3 more
doaj +1 more source
The synthesis of lignans and lignan analogs
In this thesis 'E,E'-dibenzylidenesuccinates were shown to exhibit atropisomerism, enantiomerism that originates from hindered rotation about the butadiene carbon - carbon single bond. In addition, the 'E,E'-dibenzylidenesuccinates were found to undergo photochemical electrocyclic reactions and thermal 1,5-sigmatropic hydrogen shifts to give 'cis'-1,2 ...
openaire +1 more source
Polygonati Rhizoma Attenuates Oxidative Stress‐Induced Senescence in Periodontal Ligament Stem Cells
Network pharmacology identified the potential targets and pathways of Polygonati Rhizoma (PR) against aging‐related periodontitis through PPI, GO/KEGG enrichment, and molecular docking. Experimental validation in a D‐galactose‐induced senescence model of periodontal ligament stem cells showed that PR‐medicated serum attenuated cellular senescence and ...
Xinran Feng +6 more
wiley +1 more source
Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao +4 more
wiley +1 more source

