Results 141 to 150 of about 49,716 (300)
Michael Hattaway's Introduction to this bestselling edition of As You Like It accounts for what makes this popular play both innocent and dangerous. This third edition includes a new section on recent critical interpretations, including sections on ecocriticism, peace studies, and myths of gender, on recent as well as past stage productions and films ...
openaire +2 more sources
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Uncanny Valley in Conversation? Effects of Internal and External Human-Likeness on Intimacy and Trust. [PDF]
Jang J, Lee JG, Song H.
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Left fusiform BOLD responses are inversely related to word-likeness in a one-back task
Although its precise functional contribution to reading remains unclear, there is broad consensus that an activity in the left mid-fusiform gyrus is highly sensitive to written words and word-like stimuli.
Zevin, Jason D. +4 more
core
Industrial Robot Movements, Human-Likeness & Preference
In order to understand how specific movements of industrial robots lead to perception of human likeness and preferences, we conducted an online experiment with 100 participants, recruited using Prolific.
Hostettler, Damian
core +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Voice perception reflects graded sensitivity to acoustic cues along the auditory hierarchy. [PDF]
Hect JL +4 more
europepmc +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source

