Results 141 to 150 of about 169,955 (305)
Individual differences in musical melody perception moderate the speech-to-song illusion in Mandarin Chinese listeners. [PDF]
Sci RepRathcke TV, Canzi M.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Drug-likeness prioritised selection identifies anti-<i>Escherichia coli</i> candidates confirmed by molecular docking, dynamics simulations, and antibacterial assays. [PDF]
J Enzyme Inhib Med ChemYu B, Zhu H, Xu L, Zhao X, Shi W.
europepmc +1 more source
Like Daughter, Like Mother [PDF]
The Primary Care Companion For CNS Disorders, 2006 openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
De novo covalent drug generation with enhanced drug-likeness and safety. [PDF]
Commun BiolZhang W +6 more
europepmc +1 more source
Trinitarian Ecclesiology and the Search for Unity. A Reformed Reading of Miroslav Volf [PDF]
, 2009 Brink, G. van den
core +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source