Results 231 to 240 of about 23,016,441 (309)

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Abnormal cerebellar activity and connectivity alterations of the cerebellar-limbic system in post-stroke cognitive impairment: a study based on resting state functional magnetic resonance imaging. [PDF]

Front Neurosci
Zhang H, Lu J, Zhang L, Hu J, Yue J, Ma Y, Yao Q, Jie P, Fan M, Fang J, Zhao J.   +10 more
europepmc   +1 more source

The role of limbic system irritability in linking history of childhood maltreatment and psychiatric outcomes in low-income, high-risk women: Moderation by FK506 binding protein 5 haplotype

Development and Psychopathology, 2012
Melissa N. Dackis, F. Rogosch, A. Oshri, D. Cicchetti   +3 more
semanticscholar   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Designing a Vibrotactile Feedback System for Use in Lower-Limb Prostheses: Exploring the Tactor Configuration Variables

, 2017
Sam Shi
openalex   +1 more source

The limbic system

, 2018
What is the limbic system; what are the key brain areas involved, and what do they do? This encylopedia entry gives the reader a brief overview of this key neural system and of several clinical conditions marked by limbic disorder.
openaire  

Forelimb Motor Learning and Memory Consolidation Drives Distinct Oligodendrocyte Plasticity to Regulate Task‐related Neuronal Activity

Advanced Science, EarlyView.
Genetic and chemical tracking of oligodendrogenesis, combining fiber photometric neuronal activity recording, reveals that distinct oligodendrocyte plasticities are adopted during different phases of motor learning to fine‐tune task‐related neuronal activity, with a preferential involvement of oligodendrogenesis suppression and node lengthening (type 2
Shuming Wang, Nuo Xu, Wenwen Wang, Yongxiang He, Yuqian Yang, Liuning Zhang, Yanping Zou, Yuehua He, Huiliang Li, Liang Gao, Lin Xiao   +10 more
wiley   +1 more source

Tracts in the limbic system show microstructural alterations post COVID-19 recovery. [PDF]

Brain Commun
Mishra SS, Pedersini CA, Misra R, Gandhi TK, Rokers B, Biswal BB.   +5 more
europepmc   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source

Functional status of the cardiovascular system in the wounded with limb injuries at the levels of health care according to tetrapolar rheography

, 2019
И. П. Хоменко, S. О. Коrol, А. А. Kozhokaru, B. V. Matviichuk, Р. М. Січинава   +4 more
openalex   +2 more sources