The compositional meaning of a detection limit
Conclusions The chemical interpretation of the detection limit and its stochastic model counterpart has thus different consequences for the statistical analysis than we would expect from the word by word interpretation of “below detection limit” as a concentration below some limit.
Boogaart, K. Gerald van den +2 more
openaire +4 more sources
555 Flow cytometry-based lower limit of quantitation (LLOQ) validation for detection of DuoCAR20.19.22-D95 CAR T cells in support of a phase 1/2 clinical trial for B-cell malignancies [PDF]
Nassouh Mourabet +10 more
openalex +1 more source
Pushing The Limits Of Detection Of Weak Binding Using Fragment Based Drug Discovery: Identification Of New Cyclophilin Binders [PDF]
C. Georgiou +5 more
openalex +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
To pool or not to pool, from whether to when: applications of pooling to biospecimens subject to a limit of detection [PDF]
Enrique F. Schisterman, Albert Vexler
openalex +1 more source
Review of: "Limit of detection in different matrices of nineteen commercially available rapid antigen tests for the detection of SARS-CoV-2" [PDF]
Danila Moscone
openalex +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Solid contact Zn2+ -selective electrode with low detection limit and stable and reversible potential [PDF]
Cecylia Wardak
openalex +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Limits of Detection and Limits of Infection: Quantitative HIV Measurement in the Era of U = U
Ethel D. Weld
openalex +2 more sources

