Results 111 to 120 of about 5,298,176 (299)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Exploring the origins of high-velocity features in SNe Ia with the spectral synthesis code TARDIS

open access: yesAstronomy & Astrophysics
Appearing as secondary higher-velocity absorption components, high-velocity features (HVFs) have been observed in several absorption lines in many Type Ia supernovae (SNe Ia). The frequency and ubiquity of these components in silicon and calcium features
Harvey L.   +10 more
doaj   +1 more source

Jet-Induced Emission-Line Nebulosity and Star Formation in the High-Redshift Radio Galaxy 4C41.17

open access: yes, 1999
The high redshift radio galaxy 4C41.17 consists of a powerful radio source in which previous work has shown that there is strong evidence for jet-induced star formation along the radio axis.
Arjun Dey   +11 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Galaxy Evolution in a Pilot Survey up to z=1 and CDM Halos

open access: yesAdvances in Astronomy, 2011
We study spectral evolution of galaxies in a magnitude limited sample of 550 galaxies from z=1 down to z=0.3 on a pencil beam of ≈10′×10′. We concentrate on the large apparent cosmological structures along the line of sight, and we bin our individual ...
E. Giraud   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

ODIN: Improved Narrowband Lyα Emitter Selection Techniques for z = 2.4, 3.1, and 4.5

open access: yesThe Astrophysical Journal
Lyman-alpha-emitting galaxies (LAEs) are typically young, low-mass, star-forming galaxies with little extinction from interstellar dust. Their low dust attenuation allows their Ly α emission to shine brightly in spectroscopic and photometric observations,
Nicole M. Firestone   +27 more
doaj   +1 more source

The Formation of IRIS Diagnostics. IX. The Formation of the C I 135.58 Line in the Solar Atmosphere

open access: yes, 2017
The C I 135.58 line is located in the wavelength range of NASA's Interface Region Imagin Spectrograph (IRIS) small explorer mission. We here study the formation and diagnostic potential of this line by means of non local-thermodynamic-equilibrium ...
Carlsson, Mats   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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