Results 31 to 40 of about 6,338,079 (289)

Second-generation line probe assay for hepatitis C virus genotyping [PDF]

open access: yesJournal of Clinical Microbiology, 1996
Because of the enormous variability of hepatitis C virus (HCV), the development of reliable genotyping assays is a formidable challenge. The optimal genotyping region appears to be the 5' untranslated region (UR) because of high conservation within, but considerable variability between, genotypes.
L, Stuyver   +4 more
openaire   +2 more sources

Development of a PCR-Based Line Probe Assay for Identification of Fungal Pathogens [PDF]

open access: yesJournal of Clinical Microbiology, 2000
ABSTRACT We report on a reverse-hybridization line probe assay (LiPA) which when combined with PCR amplification detects and identifies clinically significant fungal pathogens including Candida , Aspergillus , and Cryptococcus species.
C, Martin   +6 more
openaire   +2 more sources

Molecular diagnosis of tuberculosis with emphasis on Xpert Mycobacterium tuberculosis assay – Clinical review

open access: yesJournal of Clinical Sciences, 2020
Tuberculosis (TB), due to Mycobacterium tuberculosis(MTB), remains a major public health issue. It causes ill health for approximately 10 million people each year and is one of the top ten causes of death worldwide.
Gajanan S Gaude, Samskruti Vishwanath
doaj   +1 more source

Discordance between GeneXpert assay and conventional drug-susceptibility testing in detecting rifampicin-resistant tuberculosis: A perspective of the line probe assay

open access: yesInternational Journal of Mycobacteriology, 2016
Background: Early detection for tuberculosis (TB) and rifampicin-resistant TB (RRTB) is crucial for proper control of this disease. WHO recommended the use of the GeneXpert assay at district level to cover these two public health demands?
Ruqaya M Ali, Ahmed A Alsudani
doaj   +1 more source

Multidrug-resistant tuberculosis detection and characterization of mutations in mycobacterium tuberculosis by genotype MTBDRplus

open access: yesIndian Journal of Pathology and Microbiology, 2017
Detection of drug resistance in Mycobacterium tuberculosis by conventional phenotypic drug susceptibility testing methods requires several weeks. Therefore, molecular diagnostic tests for rapid detection of multidrug resistance tuberculosis (MDR-TB) are ...
Rajneesh Tripathi, Shampa Anupurba
doaj   +1 more source

Comparison between the conventional method and molecular line probe assay for identification and drug sensitivity of mycobacteria tuberculosis from clinical specimens [PDF]

open access: yes, 2014
Rapid susceptibility testing of Mycobacterium tuberculosis strains is imperative for therapy selection but traditional drug susceptibility tests take weeks or are expensive. Classical drug susceptibility (DST) may take up to 2 to 4 months. The line probe
Agrawal, Nivesh   +5 more
core   +1 more source

Clinical outcomes and molecular characterization of drug-resistant tuberculosis in pre- and extensively drug-resistant disease based on line probe assays

open access: yesBrazilian Journal of Infectious Diseases, 2021
Multidrug-resistant tuberculosis (MDR-TB) represents a significant impact in transmission, outcome, and health costs. The World Health Organization recommends implementation of rapid diagnostic methods for multidrug-resistance detection.
Lauane G. Araújo   +5 more
doaj   +1 more source

Reversing the tide of tuberculosis in India: complementing microscopy with line probe assays

open access: yesGlobal Public Health, 2008
In 1993, the World Health Organisation (WHO) declared tuberculosis (TB) a global health threat, adopted the Directly Observed Therapy - Short Course (DOTS) strategy, and set two targets for control and elimination of the disease: to detect 70% of sputum smear positive cases and to successfully treat 85% of those cases.
Y Ben, Amor, M, Fraden, J, Ruxin
openaire   +2 more sources

Results of line probe assay testing by phenotypic drug susceptibility testing result.

open access: yes, 2015
INH: isoniazid; RIF: rifampin; LPA: line probe assay; MDR: multidrug-resistant; XDR: extensively drug-resistant tuberculosis. TB: tuberculosis; DST: drug-susceptibility testResults of line probe assay testing by phenotypic drug susceptibility testing ...
Neel R. Gandhi (357970)   +4 more
core   +1 more source

Diagnostic performance of genoType® MTBDRplus line probe assay in bronchoalveolar lavage for pulmonary tuberculosis diagnosis in sputum scarce and smear-negative patients

open access: yesInternational Journal of Mycobacteriology, 2017
Background: MTBDRplus line probe assay (LiPA) has been endorsed by the World Health Organization for pulmonary tuberculosis (TB) diagnosis. However, its value for Mycobacterium tuberculosis (MTB) detection in bronchoalveolar lavage (BAL) needs ...
Farah Idrees   +4 more
doaj   +1 more source

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