Results 31 to 40 of about 6,338,079 (289)
Second-generation line probe assay for hepatitis C virus genotyping [PDF]
Because of the enormous variability of hepatitis C virus (HCV), the development of reliable genotyping assays is a formidable challenge. The optimal genotyping region appears to be the 5' untranslated region (UR) because of high conservation within, but considerable variability between, genotypes.
L, Stuyver +4 more
openaire +2 more sources
Development of a PCR-Based Line Probe Assay for Identification of Fungal Pathogens [PDF]
ABSTRACT We report on a reverse-hybridization line probe assay (LiPA) which when combined with PCR amplification detects and identifies clinically significant fungal pathogens including Candida , Aspergillus , and Cryptococcus species.
C, Martin +6 more
openaire +2 more sources
Tuberculosis (TB), due to Mycobacterium tuberculosis(MTB), remains a major public health issue. It causes ill health for approximately 10 million people each year and is one of the top ten causes of death worldwide.
Gajanan S Gaude, Samskruti Vishwanath
doaj +1 more source
Background: Early detection for tuberculosis (TB) and rifampicin-resistant TB (RRTB) is crucial for proper control of this disease. WHO recommended the use of the GeneXpert assay at district level to cover these two public health demands?
Ruqaya M Ali, Ahmed A Alsudani
doaj +1 more source
Detection of drug resistance in Mycobacterium tuberculosis by conventional phenotypic drug susceptibility testing methods requires several weeks. Therefore, molecular diagnostic tests for rapid detection of multidrug resistance tuberculosis (MDR-TB) are ...
Rajneesh Tripathi, Shampa Anupurba
doaj +1 more source
Comparison between the conventional method and molecular line probe assay for identification and drug sensitivity of mycobacteria tuberculosis from clinical specimens [PDF]
Rapid susceptibility testing of Mycobacterium tuberculosis strains is imperative for therapy selection but traditional drug susceptibility tests take weeks or are expensive. Classical drug susceptibility (DST) may take up to 2 to 4 months. The line probe
Agrawal, Nivesh +5 more
core +1 more source
Multidrug-resistant tuberculosis (MDR-TB) represents a significant impact in transmission, outcome, and health costs. The World Health Organization recommends implementation of rapid diagnostic methods for multidrug-resistance detection.
Lauane G. Araújo +5 more
doaj +1 more source
Reversing the tide of tuberculosis in India: complementing microscopy with line probe assays
In 1993, the World Health Organisation (WHO) declared tuberculosis (TB) a global health threat, adopted the Directly Observed Therapy - Short Course (DOTS) strategy, and set two targets for control and elimination of the disease: to detect 70% of sputum smear positive cases and to successfully treat 85% of those cases.
Y Ben, Amor, M, Fraden, J, Ruxin
openaire +2 more sources
Results of line probe assay testing by phenotypic drug susceptibility testing result.
INH: isoniazid; RIF: rifampin; LPA: line probe assay; MDR: multidrug-resistant; XDR: extensively drug-resistant tuberculosis. TB: tuberculosis; DST: drug-susceptibility testResults of line probe assay testing by phenotypic drug susceptibility testing ...
Neel R. Gandhi (357970) +4 more
core +1 more source
Background: MTBDRplus line probe assay (LiPA) has been endorsed by the World Health Organization for pulmonary tuberculosis (TB) diagnosis. However, its value for Mycobacterium tuberculosis (MTB) detection in bronchoalveolar lavage (BAL) needs ...
Farah Idrees +4 more
doaj +1 more source

