Results 51 to 60 of about 6,338,079 (289)

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Genotyping of Human Papillomavirus in Liquid Cytology Cervical Specimens by the PGMY Line Blot Assay and the SPF ₁₀ Line Probe Assay [PDF]

Journal of Clinical Microbiology, 2002
ABSTRACT A comparison of two PCR-based human papillomavirus (HPV) DNA detection and genotyping systems (PGMY LBA and SPF 10 LiPA) was conducted in two laboratories. Both systems are based on broad-spectrum PCR for the detection of HPV DNA, followed by reverse hybridization with type-specific probes.
Leen-Jan, van Doorn, Wim, Quint, Bernhard, Kleter, Anco, Molijn, Brigitte, Colau, Marie-Thérèse, Martin, , Kravang-In, Norah, Torrez-Martinez, Cheri L, Peyton, Cosette M, Wheeler   +9 more
openaire   +2 more sources

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Profile and Frequency of Mutations Conferring Drug-Resistant Tuberculosis in the Central, Southeastern and Eastern Ethiopia

Infection and Drug Resistance, 2023
Mulualem Agonafir,1 Gurja Belay,1 Adey Feleke,1 Nontuthuko Maningi,2 Feven Girmachew,3 Melese Reta,2,4 P Bernard Fourie2 1Department of Microbial, Cellular and Molecular Biology, College of Natural and Computational Sciences, Addis Ababa University ...
Agonafir M, Belay G, Feleke A, Maningi N, Girmachew F, Reta M, Fourie PB   +6 more
doaj  

Detection of Multi-Drug-Resistance in Extra Pulmonary Tuberculosis by Indirect GenoType MTBDRplus Line Probe Assay

RUHS Journal of Health Sciences, 2023
Introduction: Approximately 15 to 20 percent of tuberculosis patients have extra-pulmonary tuberculosis (EP-TB), which is often difficult to diagnose. Further multi drug resistant tuberculosis (MDR-TB) in EP samples has not been reported.
Sumit Goyal, Bharti Malhotra, Shipra Bhargava
doaj   +1 more source

Sensitive Line Probe Assay That Simultaneously Detects Mutations Conveying Resistance to Lamivudine and Adefovir [PDF]

Journal of Clinical Microbiology, 2006
ABSTRACT The INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the presence of lamivudine and adefovir resistance mutations in clinical samples, has a high degree of concordance with sequencing, and can ...
Hussain M., Fung S., Libbrecht E., Sablon E., Cursaro C., ANDREONE, PIETRO, Lok A. S.   +6 more
openaire   +4 more sources

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Evaluation of the MeltPro Myco Assay for the Identification of Non-Tuberculous Mycobacteria

Infection and Drug Resistance, 2022
Jian Lin,1,2 Yong Zhao,1,2 Shuzhen Wei,1,2 Zhisong Dai,1,2 Shufang Lin1,2 1Institute of Tuberculosis Control and Prevention, Fujian Center for Disease Control and Prevention, Fuzhou, People’s Republic of China; 2Fujian Provincial Key Laboratory of ...
Lin J, Zhao Y, Wei S, Dai Z, Lin S
doaj  

Evaluation of Geno Type MTBDRplus Line Probe Assay for Early Detection of Drug Resistance in Tuberculous Meningitis Patients in India

Journal of Global Infectious Diseases, 2015
Background: Molecular methods which allow for rapid and reliable detection of drug resistance have yet not been sufficiently evaluated for timely management of patients with tuberculous meningitis.
Renu Gupta, Rajeev Thakur, Prerna Gupta, Nupur Jalan, Suman Kushwaha, Meena Gupta, Piyush Gupta, Amitesh Aggarwal, Vikas Manchanda   +8 more
doaj   +1 more source

Evaluation of rapid diagnostic tests and assessment of risk factors in drug-resistant pulmonary tuberculosis

Journal of Family Medicine and Primary Care, 2020
Background: Early diagnosis and treatment of drug-resistant tuberculosis (TB) is crucial to halt the spread of drug resistance in the community. Aim: The aim of the study was to compare rapid diagnostic tests (GeneXpert and line probe assay, LPA) with ...
Vimal Kumar, Pankaj Jorwal, Manish Soneja, Sanjeev Sinha, Neeraj Nischal, Prayas Sethi, Saikat Mondal, Zia Abdullah, R M Pandey   +8 more
doaj   +1 more source