Results 71 to 80 of about 6,005,333 (282)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Verificación de calidad de modelos en regresión lineal software estadístico de regresión erla [PDF]

, 2011
En un análisis de Regresión Lineal, existen varios supuestos o premisas que deben ser considerados al momento de determinar la validez de un modelo, puesto que el no cumplimiento de alguno de estos supuestos podría conducirnos a modelos inestables, de ...
Buenaño Cordero, Juan Carlos, De La Cruz Cedeño, Celia, Zurita Herrera, Gaudencio   +2 more
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Comparative Evaluation of Two Analytical Functions for the Microdosimetry of Ions from ¹H to ²³⁸U

Quantum Beam Science
The analytical microdosimetric function (AMF) implemented in the Monte Carlo code PHITS is a unique tool that bridges the gap between macro- and microscopic scales of radiation interactions, enabling accurate microdosimetric calculations over macroscopic
Alessio Parisi, Keith M. Furutani, Tatsuhiko Sato, Chris J. Beltran   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

A Blueprint for Ocean Energy Development 2010-2015 [PDF]

In an effort to foster a collaborative approach to advancing the ocean energy industry, OWET convened the OWET 2010 Developersʼ Summit on September 27 and 28, 2010 in Portland, Oregon.
Oregon Wave Energy Trust
core   +5 more sources

Independencia Lineal

, 2014
Objeto de aprendizaje: Presentación multimediaEn este recurso se habla sobre independencia lineal, se muestran ejemplos e interpretación gráfica.1. Introducción1.1. Definición1.2. Ejemplo1.3. Teorema2. Actividad3. Bibliografía1.0This resource talks about
Palma Vanegas, Nelly Paola
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Scenarios for a Clean Energy Future: Interlaboratory Working Group on Energy-Efficient and Clean-Energy Technologies

, 2000
This study estimates the potential for public policies and R and D programs to foster clean energy technology solutions to the energy and environmental challenges facing the nation.
The Interlaboratory Working Group on Energy-Efficient and Clean-Energy Technologies
core   +1 more source