Results 81 to 90 of about 3,251,267 (306)
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Linear and Non-Linear Regression: Powerful and Very Important Forecasting Methods [PDF]
Regression Analysis is at the center of almost every Forecasting technique, yet few people are comfortable with the Regression methodology. We hope to improve the level of comfort with this article.
Athanasios VASILOPOULOS
doaj
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
ON THE GASTALDI – D’URSO FUZZY LINEAR REGRESSION [PDF]
In the crisp regression models, the differences between observed values and calculates ones are suspected to be caused by random distributed errors, although these are due to observation errors and an unappropriate model structure.
DANA-FLORENTA SIMION +2 more
doaj
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
ANALYSIS OF DISCRETE DATA USING LINEAR REGRESSION
Maximum likelihood estimates are obtained for a linear regressio model where the dependent variable is a linear transformation of mutinomially distributed random variables.
Robert J. Flowers
doaj +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
On identification methods of linear regression models
The aim of this paper is to discus the efficiency of the least squares and least absolute values estimation methods, in such situations, then the sample is with outliers, the variance of the residuals changes in the time and the residuals are correlated.
Romualdas Salėtis
doaj +1 more source

