Results 81 to 90 of about 194,123 (316)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Distributed Estimation and Control in Networked Systems [PDF]

open access: yes, 2006
Rapid advances in information processing, communication and sensing technologies have enabled more and more devices to be provided with embedded processors, networking capabilities and sensors.
Gupta, Vijay, Vijay Gupta
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Minimum attention control for linear systems : a linear programming approach

open access: yes, 2014
In this paper, we present a novel solution to the minimum attention control problem for linear systems. In minimum attention control, the objective is to minimise the ‘attention’ that a control task requires, given certain performance requirements. Here,
Heemels, W.P.M.H.   +2 more
core   +1 more source

Disturbance Decoupling of Switched Linear Systems [PDF]

open access: yes, 2010
In this paper we consider disturbance decoupling problems for switched linear systems. We will provide necessary and sufficient conditions for three different versions of disturbance decoupling, which differ based on which signals are considered to be ...
Yurtseven, E.   +8 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

H2 Guaranteed Cost Control For Uncertain Continuous-time Linear Systems

open access: yes, 2015
This paper proposes a solution to the H2 guaranteed cost control problem for uncertain, continuous-time linear systems. It consists of the determination of a constant state feedback stabilizing matrix gain and a H2-norm upper bound, valid for all ...
Geromel J.C., Souza S.R., Peres P.L.D.
core   +1 more source

Hierarchies, Spikes, and Hybrid Systems: Physiologically Inspired Control Problems [PDF]

open access: yes, 2011
In animal motor control and locomotion, neurons process information, muscles are the actuators, and the body is the plant. Control theory is the standard mathematical language for describing motor control and locomotion, but many phenomena in ...
Lamperski, Andrew G.
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Predictive pole-placement control with linear models [PDF]

open access: yes, 2002
The predictive pole-placement control method introduced in this paper embeds the classical pole-placement state feedback design into a quadratic optimisation-based model-predictive formulation. This provides an alternative to model-predictive controllers
Ronco, E., Gawthrop, P.J.
core   +1 more source

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