Results 91 to 100 of about 194,123 (316)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Robust H∞ Consensus Control for Linear Discrete-Time Swarm Systems with Parameter Uncertainties and Time-Varying Delays

open access: yesInternational Journal of Aerospace Engineering, 2019
Robust H∞ consensus control problems of linear swarm systems with parameter uncertainties and time-varying delays are investigated. In this literature, a linear consensus protocol for high-order discrete-time swarm systems is proposed.
Xiao Jia, Laihong Hu, Fujun Feng, Jun Xu
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Stabilization of discrete linear repetitive processes with switched dynamics

open access: yes, 2006
Repetitive processes are a distinct class of 2D systems (i.e. information propagation in two independent directions) of both systems theoretic and applications interest.
Bachelier, O   +11 more
core   +1 more source

Synthesis of distributed robust H-Infinity controllers for interconnected discrete time systems [PDF]

open access: yes, 2016
This paper presents an algorithm for the synthesis of robust distributed controllers for interconnected linear discrete-time systems. For a network of interconnected uncertain linear time-invariant systems, the distributed controller achieves robust ...
Weiland, S Siep   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Upcoming numerical linear algebra issues in systems and control theory

open access: yes, 1992
We discuss a number of novel issues in the interdisciplinary area of numerical linear algebra and systems and control theory. Although we do not claim to be exhaustive we give a number of upcoming issues" which we believe will play an important role in ...
IFAC workshop on Mutual Impact of Computing Power and Control Theory   +1 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Chattering Free Control Of Continuous-time Switched Linear Systems

open access: yes, 2015
Chattering is an undesirable phenomenon characterised by infinitely fast switching which may cause equipment damage in real systems. To avoid its occurrence, this study proposes a chattering-free switching strategy for continuous-time switched linear ...
Geromel J.C.   +5 more
core   +1 more source

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