Results 91 to 100 of about 118,761,980 (258)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
What can systems and control theory do for agricultural science? [PDF]
: While many professionals with a background in agricultural and bio-resource sciences work with models, only few have been exposed to systems and control theory.
Straten, G., van, van Straten, G.
core
Synthesis of distributed robust H-Infinity controllers for interconnected discrete time systems [PDF]
This paper presents an algorithm for the synthesis of robust distributed controllers for interconnected linear discrete-time systems. For a network of interconnected uncertain linear time-invariant systems, the distributed controller achieves robust ...
Weiland, S Siep +3 more
core +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Upcoming numerical linear algebra issues in systems and control theory
We discuss a number of novel issues in the interdisciplinary area of numerical linear algebra and systems and control theory. Although we do not claim to be exhaustive we give a number of upcoming issues" which we believe will play an important role in ...
IFAC workshop on Mutual Impact of Computing Power and Control Theory +1 more
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Iterative Learning Control (ILC) is now well established in terms of both the underlying theory and experimental application. This approach is specifically targeted at cases where the same operation is repeated over a finite duration with resetting ...
Rogers, E +3 more
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Compositional Analysis for Linear Control Systems [PDF]
The complexity of physical and engineering systems, both in terms of the governing physical phenomena and the number of subprocesses involved, is mirrored in ever more complex mathematical models.
Kerber, Florian, +7 more
core +2 more sources
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

