Results 41 to 50 of about 4,000 (171)

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, Volume 13, Issue 37, 3 July 2026.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

BioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen, Thomas Roeder, Gerald Rimbach   +2 more
wiley   +1 more source

Optimization of High Yield Conditions and Antioxidant Activity of Ganoderma lingzhi Exopolysaccharide Promoted by Vernonia amygdalina Leaf

Shipin gongye ke-ji
Exopolysaccharide (EPS) is the main active metabolite of Ganoderma lingzhi in liquid fermentation. In order to increase the content of Ganoderma lingzhi EPS, this study added Vernonia amygdala leaf powder to the fermentation medium, and used single ...
Kunpeng TANG, Shengrong LIU, Mingming YU, Liyun YE, Shengyou WANG, Xiaoping WU   +5 more
doaj   +1 more source

Misperception of Extreme Weather Event Mortality Risk in the United States

GeoHealth, Volume 10, Issue 7, July 2026.
Abstract Communicating the risks posed by extreme weather events remains a challenge for researchers and policy makers. This study evaluates the gap between public perceptions on climate risk and scientific estimates of mortality burden from climate‐related extreme weather events.
Mitchell Manware, Lingzhi Chu, Ying Hu, Jennifer Marlon, Anthony Leiserowitz, Kai Chen   +5 more
wiley   +1 more source

Effect of thermal-oxidative aging on cellular structure and properties of silicone rubber foams

Hecheng xiangjiao gongye, 2022
The aging properties of silicon rubber foam (SRF) were studied by using thermal-oxidative accelerated aging method, and the influence law of different aging time on cellular structure and properties of SRF was explored.
JI Shi-chen; JIANG Bai-yu; GAO Wei; WU Qiang; CHEN Shi-long; ZHANG Chun-hui; YANG Cheng
doaj   +1 more source

Stress Testing Hydropower Operation Under Variable Renewable Energy Integration: Potential Impacts and Dynamically Adaptive Strategies

Water Resources Research, Volume 62, Issue 7, July 2026.
Abstract Hydropower with reservoir offers a compelling combination of stability and flexibility services for regional socio‐economic development and power system. However, its operational paradigm is poorly characterized in the rapidly evolving power system, missing opportunities to effectively balance variable renewable energy (VRE) integration and ...
Xiaoyu Jin, Xiangyang Hu, Chuntian Cheng, Lingzhi Yan, Shubing Cai, Zhipeng Zhao   +5 more
wiley   +1 more source

Identifying the “Mushroom of Immortality”: Assessing the Ganoderma Species Composition in Commercial Reishi Products

Frontiers in Microbiology, 2018
Species of Ganoderma, commonly called reishi (in Japan) or lingzhi (in China), have been used in traditional medicine for thousands of years, and their use has gained interest from pharmaceutical industries in recent years.
Andrew L. Loyd, Brantlee S. Richter, Michelle A. Jusino, Camille Truong, Camille Truong, Matthew E. Smith, Robert A. Blanchette, Jason A. Smith   +7 more
doaj   +1 more source

Efficacy and Safety of L‐Carnosine‐Containing Hyaluronate Injection for Facial Skin Hydration and Brightness: A Randomized, Controlled, Evaluator‐Blinded Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background L‐carnosine, a dipeptide with superior antioxidant and antiglycation properties, serves as the core active component in this study. We aimed to evaluate the efficacy and safety of a novel injectable composite solution, which features L‐carnosine in combination with non‐crosslinked sodium hyaluronate, glycine, alanine, proline, and ...
Zhanhong Li, Jingfang Sun, Zhehu Jin, Wei Guo, Aili Cui, Huaigu Wang, Jiahua Wang, Xiaoyi Qiu, Heyang Xi, Yao Zhang, Lu Zhang, Ligen Xuan, Lingzhi Shi, Yangliang Yi, Huiyin Qiu, Fangke Guan, Yaling Xie, Zhouwei Liu, Lili Liang, Haijun Yang, Chunfang Chen, Huiying Wang, Xiaoling Sun, Fengsheng Che, Qiong Meng   +24 more
wiley   +1 more source

Swelling‐Induced Stress‐Assisted Transfer of Nanodiamond Arrays With a PVA Carrier Tape for Conformal Bio‐Integrated Sensing and Labelling

Advanced Functional Materials, Volume 36, Issue 50, 22 June 2026.
This work introduces a swelling‐induced, stress‐assisted water‐soluble PVA tape strategy to transfer‐print nanodiamond quantum‐sensor arrays onto soft, curved biological interfaces. The room‐temperature, water‐triggered process achieves >98% fidelity and residue‐free integration, enabling conformal quantum sensing on contact lenses, neural probes, and ...
Luyao Zhang, Lingzhi Wang, Xinhao Hu, Tai Nam Yip, Mingze Sun, Jixiang Jing, Lizhi Xu, Yuan Lin, Yong Hou, Zhiqin Chu   +9 more
wiley   +1 more source

Improved Production and Antitumor Properties of Triterpene Acids from Submerged Culture of Ganoderma lingzhi

Molecules, 2016
Triterpene acids (TAs) are the major bioactive constituents in the medicinal fungus Ganoderma lingzhi. However, fermentative production of TAs has not been optimized for commercial use, and whether the TAs isolated from G.
Xiao-Ling Wang, Zhong-Yang Ding, Gao-Qiang Liu, Hailong Yang, Guo-Ying Zhou   +4 more
doaj   +1 more source