Results 151 to 160 of about 199,519 (335)

Additional file 3: ExampleData_GxE_1.01_210corr_840noise. of Detection of gene-environment interactions in the presence of linkage disequilibrium and noise by using genetic risk scores with internal weights from elastic net regression

, 2017
Anke Hüls, Katja Ickstadt, Tamara Schikowski, Ursula Krämer   +3 more
openalex   +1 more source

Genome-wide patterns of segregation and linkage disequilibrium: the construction of a linkage genetic map of the poplar rust fungus Melampsora larici-populina [PDF]

, 2014
Michaà l Pernaci, Stéphane De Mita, Axelle Andrieux, Jérémy Pétrowski, Fabien Halkett, Sébastien Duplessis, Pascal Frey   +6 more
openalex   +1 more source

Genome-Wide Scanning Enabled SNP Discovery, Linkage Disequilibrium Patterns and Population Structure in a Panel of Fonio (Digitaria exilis [Kippist] Stapf) Germplasm

, 2021
Abdou R. Ibrahim Bio Yerima, Kassari Ango Issoufou, Charlotte A. Adje, Aïssata Mamadou, Happiness Ogba Oselebe, Mame Codou Guèye, Claire Billot, Enoch G. Achigan‐Dako   +7 more
openalex   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

QTL Identification Using Combined Linkage and Linkage Disequilibrium Mapping for Milk Production Traits on BTA6 in Chinese Holstein Population [PDF]

, 2010
Fang Hu, J. F. Liu, Zhao‐Bang Zeng, Xiangdong Ding, C. C. Yin, Yiwen Gong, Q. Zhang   +6 more
openalex   +1 more source

Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

International Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago, Efthymios Ladoukakis, Dorota Scibior‐Bentkowska, Belinda Nedjai   +3 more
wiley   +1 more source

Interplay Between Green Investment and Market Price Premia in Global Shipping

International Journal of Finance &Economics, EarlyView.
ABSTRACT Existing research emphasises that the driver of green investment is its future profitability. This paper shows that other investors' decisions also influence green investment. We take the example of scrubber installation in shipping, which is optional by regulation but has an established market for trading its underlying asset.
Yao Shi, Nikos C. Papapostolou, Malvina Marchese, Ioannis C. Moutzouris, Angelos Efstathiou   +4 more
wiley   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Sampling distribution of summary linkage disequilibrium measures [PDF]

, 2002
M. Dawn Teare, Alison M. Dunning, F. DUROCHER, Gadi Rennart, Douglas F. Easton   +4 more
openalex   +1 more source

Move beyond free radical theory of aging

iMetaOmics, EarlyView.
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley   +1 more source