Results 11 to 20 of about 199,519 (335)

LDmat: efficiently queryable compression of linkage disequilibrium matrices. [PDF]

Bioinformatics, 2023
Weiner RJ, Lakhani C, Knowles DA, Gürsoy G.   +3 more
europepmc   +2 more sources

Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE [PDF]

Genome Biology
Uncovering environmental factors interacting with genetic factors to influence complex traits is important in genetic epidemiology and disease etiology. We introduce BiVariate Linkage-Disequilibrium Eigenvalue Regression for Gene-Environment interactions
Zihan Dong, Wei Jiang, Jiangnan Shen, Hongyu Li, Yuhan Xie, Andrew T. DeWan, Hongyu Zhao   +6 more
doaj   +2 more sources

The Genetic Architecture of Juvenile Growth Traits in the Conifer Torreya grandis as Revealed by Joint Linkage and Linkage Disequilibrium Mapping

Frontiers in Plant Science, 2022
Despite its high economical and ornamental values, Torreya grandis, a dioecious non-timber coniferous species, has long been an underrepresented species.
Wenchong Chen, Weiwu Yu, Ang Dong, Yanru Zeng, Huwei Yuan, Bingsong Zheng, Rongling Wu, Rongling Wu   +7 more
doaj   +1 more source

Visualization of pairwise and multilocus linkage disequilibrium structure using latent forests. [PDF]

PLoS ONE, 2011
Linkage disequilibrium study represents a major issue in statistical genetics as it plays a fundamental role in gene mapping and helps us to learn more about human history.
Raphaël Mourad, Christine Sinoquet, Christian Dina, Philippe Leray   +3 more
doaj   +1 more source

Linkage Disequilibrium between LDLR rs688 and AvaII Genes and its Significant Association with Ischemic Stroke

Journal of Integrative Neuroscience, 2023
Background: To analyze the polymorphism distribution of low density lipoprotein receptor rs688, AvaII, NcoI gene in ischemic stroke, and explore the linkage disequilibrium among them. The correlation between the linkage disequilibrium and ischemic stroke
Yabin Chen, Hehui Cai, Jianming Zhang, Yongfa Su, Yibo Wu, Zhenzhong Lin, Zhishan Zhang   +6 more
doaj   +1 more source

Discovery of mating in the major African livestock pathogen Trypanosoma congolense [PDF]

, 2009
The protozoan parasite, Trypanosoma congolense, is one of the most economically important pathogens of livestock in Africa and, through its impact on cattle health and productivity, has a significant effect on human health and well being.
A MacLeod, A MacLeod, A Tait, A Tait, A Tait, AC Hoare, AL Hughes, Alana Black, Alison Tweedie, AM Schurko, Andreas Schoenefeld, Andy Tait, Annette MacLeod, B Haubold, C. Michael R. Turner, Christiane Hertz-Fowler, CJ Young, D Faye, DK Masiga, DL Hartl, DR Page, F Balloux, FG Razakandrainibe, G Benson, G Evanno, Gina L. Pinchbeck, GL Pinchbeck, J Maynard Smith, J Sternberg, JK Gashumba, JK Pritchard, JR Stevens, JR Stevens, K Lewicka, Laurent Rénia, Liam J. Morrison, LJ Morrison, LJ Morrison, LJ Morrison, M Hope, M Koffi, M Raymond, M Tibayrenc, M Tibayrenc, M Tibayrenc, MA Ramesh, MW Gaunt, NM El-Sayed, P Stenberg, PH Holmes, PMA Shaw, R Peakall, Robert M. Christley, S Geerts, T de Meeus, T Mzilahowa, TJ Anderson, V Jamonneau, W Gibson, W Gibson, W Gibson, W Gibson, W Weir, WP Hedrick   +63 more
core   +17 more sources

Disequilibrium linkage (gametic disequilibrium) of structural genes in the bovine population

Аграрная наука Евро-Северо-Востока, 2021
In the population of Kholmogor cattle (n=824), gametic disequilibrium was studied for alleles of the polymorphic loci β-Lg (LGB), β-Cn (CSN2) and æ-Cn (CSN3). In purebred Kholmogor cattle, the β-casein polymorphism is determined by three alleles with the
V. S. Matyukov, V. G. Zainullin
doaj   +1 more source

Extent of third-order linkage disequilibrium in a composite line of Iberian pigs

BMC Genetics, 2018
Background Previous studies on linkage disequilibrium have investigated second order linkage disequilibrium in animal and plant populations. The objective of this paper was to investigate the genome-wide levels of third order linkage disequilibrium in a ...
Luis Gomez-Raya, Luis Silio, Wendy M. Rauw, Luis Alberto Gracia-Cortés, Carmen Rodríguez   +4 more
doaj   +1 more source

A Novel Method for Mendelian Randomization Analyses With Pleiotropy and Linkage Disequilibrium in Genetic Variants From Individual Data

Frontiers in Genetics, 2021
Mendelian randomization makes use of genetic variants as instrumental variables to eliminate the influence induced by unknown confounders on causal estimation in epidemiology studies.
Yuquan Wang, Tingting Li, Liwan Fu, Siqian Yang, Yue-Qing Hu, Yue-Qing Hu   +5 more
doaj   +1 more source

Accurate Estimation of Effective Population Size in the Korean Dairy Cattle Based on Linkage Disequilibrium Corrected by Genomic Relationship Matrix [PDF]

Asian-Australasian Journal of Animal Sciences, 2013
Linkage disequilibrium between markers or genetic variants underlying interesting traits affects many genomic methodologies. In many genomic methodologies, the effective population size (Ne) is important to assess the genetic diversity of animal ...
Dong-Hyun Shin, Kwang-Hyun Cho, Kyoung-Do Park, Hyun-Jeong Lee, Heebal Kim   +4 more
doaj   +1 more source