Results 21 to 30 of about 199,519 (335)

Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study [PDF]

, 2005
Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term disability.
Bukulmez, H, Colbert, RA, Elston, RC, Fife, M, Glass, DN, Olson, JM, Thompson, SD, Tsoras, M, Twine, NA, Woo, P   +9 more
core   +2 more sources

Division of linkage disequilibrium between absolute linkage disequilibrium and linkage equilibrium [PDF]

Journal of Human Genetics, 2005
Linkage disequilibrium is the association between alleles in the allele distributions across linked loci and is intermediate in character between the dependence and the independence of allele distribution. This ambivalence makes linkage disequilibrium difficult to understand and to treat mathematically.
openaire   +2 more sources

Genomic signatures of population decline in the malaria mosquito Anopheles gambiae [PDF]

, 2016
Population genomic features such as nucleotide diversity and linkage disequilibrium are expected to be strongly shaped by changes in population size, and might therefore be useful for monitoring the success of a control campaign.
A De, AD Stump, Austin Burt, CG Nevill, Charles Mbogo, D Bachtrog, EA Okiro, F Tajima, F Tajima, Franklin Mosha, G McVean, GA Watterson, H Li, H Li, H Li, Janet Midega, JH Gillespie, JK Pritchard, JM Mwangangi, K Tamura, K Thornton, KA Lindblade, M Kirin, M Pombi, MN Bayoh, NJ Govella, P Andolfatto, PC Kipyab, PP Chaki, PR Haddrill, RF Daniels, RN Gutenkunst, RR Hudson, S Schiffels, Samantha M. O’Loughlin, SC Nkhoma, SM O’Loughlin, Stephen M. Magesa, TL Russell, WG Hill   +39 more
core   +5 more sources

Genome resequencing reveals multiscale geographic structure and extensive linkage disequilibrium in the forest tree Populus trichocarpa [PDF]

, 2009
This is the publisher’s final pdf. The article is copyrighted by the New Phytologist Trust and published by John Wiley & Sons, Inc. It can be found at: http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291469-8137.
Slavov, Gancho Trifonu, Difazio, Stephen P., Martin, Joel, Schackwitz, Wendy, Muchero, Wellington, Rodgers-Melnick, Eli, Lipphardt, Mindie F., Pennacchio, Christa P., Hellsten, Uffe, Pennacchio, Len A., Gunter, Lee E., Ranjan, Priya, Vining, Kelly, Pomraning, Kyle R., Wilhelm, Larry J., Pellegrini, Matteo, Mockler, Todd C., Freitag, Michael, Geraldes, Armando, El-Kassaby, Yousry A., Mansfield, Shawn D., Cronk, Quentin C. B., Douglas, Carl J., Strauss, Steven H., Rokhsar, Dan, Tuskan, Gerald A.   +25 more
core   +4 more sources

MIDAS: software for analysis and visualisation of interallelic disequilibrium between multiallelic markers

BMC Bioinformatics, 2006
Background Various software tools are available for the display of pairwise linkage disequilibrium across multiple single nucleotide polymorphisms. The HapMap project also presents these graphics within their website.
Day Ian NM, Zapata Carlos, Rodriguez Santiago, Gaunt Tom R   +3 more
doaj   +1 more source

Whole genome linkage disequilibrium maps in cattle

BMC Genetics, 2007
Background Bovine whole genome linkage disequilibrium maps were constructed for eight breeds of cattle. These data provide fundamental information concerning bovine genome organization which will allow the design of studies to associate genetic variation
Mannen Hideyuki, Gao Chuan, Gill Clare A, Neto Emmanuel, Crews Denny, Coppieters Wouter, Aerts Jan, Matukumalli Lakshmi K, Murdoch Brenda M, Schnabel Robert D, McKay Stephanie D, Stothard Paul, Wang Zhiquan, Van Tassell Curt P, Williams John L, Taylor Jeremy F, Moore Stephen S   +16 more
doaj   +1 more source

A linkage disequilibrium-based approach to selecting disease-associated rare variants.

PLoS ONE, 2013
Rare variants have increasingly been cited as major contributors in the disease etiology of several complex disorders. Recently, several approaches have been proposed for analyzing the association of rare variants with disease.
Rajesh Talluri, Sanjay Shete
doaj   +1 more source

Bayesian estimates of linkage disequilibrium

BMC Genetics, 2007
Background The maximum likelihood estimator of D' – a standard measure of linkage disequilibrium – is biased toward disequilibrium, and the bias is particularly evident in small samples and rare haplotypes.
Abad-Grau María M, Sebastiani Paola
doaj   +1 more source

Short communication: Characterization of the genome-wide linkage disequilibrium in 2 divergent selection lines of dairy cows [PDF]

, 2010
The objective of this study was to describe results of a genome-wide map of single nucleotide polymorphisms (SNP) and assess the linkage disequilibrium (LD) level in 2 divergent selection lines of dairy cows. DNA extracted from 299 Holstein cows was used
Banos, G., Coffey, M. P.
core   +1 more source

Linkage disequilibrium fine mapping of quantitative trait loci: A simulation study

Genetics Selection Evolution, 2003
Recently, the use of linkage disequilibrium (LD) to locate genes which affect quantitative traits (QTL) has received an increasing interest, but the plausibility of fine mapping using linkage disequilibrium techniques for QTL has not been well studied ...
Pérez-Enciso Miguel, Cierco-Ayrolles Christine, Goffinet Bruno, Abdallah Jihad M   +3 more
doaj   +1 more source